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. Author manuscript; available in PMC: 2019 Apr 18.
Published in final edited form as: J Thromb Haemost. 2018 Aug 13;16(10):2083–2096. doi: 10.1111/jth.14240

Fig. 4.

Fig. 4.

Phox-I inhibition of platelet aggregation is surmountable. Phox-I was added to platelets 2 min prior to addition of CRP (left panels) or thrombin (right panels) and aggregation was recorded using a Chrono-Log Aggregometer. Phox-I inhibited aggregation induced by CRP or thrombin. Increase in CRP or thrombin concentrations gradually reversed the inhibitory effect of Phox-I. The aggregation tracings are representative of three experiments. CRP, collagen-related peptide. [Color figure can be viewed at wileyonlinelibrary.com]