Table 1.
Summary of skeletal muscle conductivity values reported at 50 kHz.
Model (strain) |
Time point | Muscle | Direction | Conductivity (S m−1) |
|
---|---|---|---|---|---|
Li et al.30 | WT (C57Bl/6N) | 10 weeks | Mouse gastrocnemius | L | 0.5 |
T | 0.15 | ||||
ALS (SOD1*G93A) | 18 weeks | L | 0.5 | ||
T | 0.3 | ||||
MDX (10ScSn-DMDmdx/J) | 10 weeks | L | 0.7 | ||
T | 0.4 | ||||
Epstein et al.31 | WT (n.a.) | n.a. | Canine adductor magnus et brevis | L | 0.7 |
T | 0.1 | ||||
Sanchez et al.43 | WT (Wistar) | 14 weeks | Rat gastrocnemius | L | 0.6 |
T | 0.25 | ||||
Rush et al.46 | WT (Mongrel) | 14–30 kg | Canine longissimus dorsi, spinalis dorsi et cervicis | L | 0.35–0.81 |
T | 0.04–0.1 | ||||
Ahad et al.47 | WT (Wistar) | 140–160 g | Rat immature gastrocnemius | L | 0.44 ± 0.04 |
T | 0.12 ± 0.01 | ||||
420–480 g | Rat mature gastrocnemius | L | 0.38 ± 0.02 | ||
T | 0.15 ± 0.01 | ||||
ALS (SOD1*G93A) | 8 weeks | Mouse gastrocnemius | L | 0.23 ± 0.05 | |
T | 0.11 ± 0.03 | ||||
18 weeks | L | 0.11 ± 0.02 | |||
T | 0.10 ± 0.01 | ||||
D2-mdx (DBA/2-congenic) | 6 weeks | Mouse gastrocnemius | L | 0.36 ± 0.03 | |
T | 0.24 ± 0.03 | ||||
10 weeks | L | 0.37 ± 0.04 | |||
T | 0.25 ± 0.01 | ||||
13 weeks | L | 0.42 ± 0.03 | |||
T | 0.33 ± 0.02 | ||||
43 weeks | L | 0.17 ± 0.01 | |||
T | 0.11 ± 0.01 | ||||
This work | WT for D2-mdx (DBA/2J) | 6 weeks | Mouse gastrocnemius | L | 0.28 ± 0.02 |
T | 0.17 ± 0.01 | ||||
13 weeks | L | 0.31 ± 0.04 | |||
T | 0.26 ± 0.03 | ||||
43 weeks | L | 0.27 ± 0.02 | |||
T | 0.13 ± 0.01 | ||||
SMA (Smn 2B/2B-Neo) | 40 weeks | Mouse gastrocnemius | L | 0.16 ± 0.02 | |
T | 0.06 ± 0.01 | ||||
DB/DB (BKS.Cg-Dock7m +/+ Leprdb/J) | 6 weeks | Mouse gastrocnemius | L | 0.31 ± 0.04 | |
T | 0.20 ± 0.04 | ||||
20 weeks | L | 0.21 ± 0.01 | |||
T | 0.09 ± 0.02 | ||||
WT for DB/DB (C57BLKS/J) | 6 weeks | Mouse gastrocnemius | L | 0.34 ± 0.02 | |
T | 0.20 ± 0.03 | ||||
20 weeks | L | 0.33 ± 0.01 | |||
T | 0.14 ± 0.02 | ||||
Mice (C57BL/6J) treated with ActRIIB-m Fc | 14 weeks | Mouse gastrocnemius | L | 0.34 ± 0.06 | |
T | 0.26 ± 0.02 |
Abbreviations: L, longitudinal; T, transverse; n.a., not available.