Table 3.

Association of Clinical and Genetic Variables With Chromosome 3 Loss^a

Variable	P Value	OR	95% CI
Clinical features
Largest basal diameter	0.015	N/A
Thickness	0.016	N/A
TNM stage	0.006	N/A
Epithelioid cells (any)	<0.001	19.07	(4.30–123.20)
Ciliary body involvement	0.131	3.96	(0.63–43.55)
Extraocular extension	0.097	∞	(0.48–∞)
Genetics—UCSF500
Mutations of relevance
GNAQ	0.198	0.47	(0.15–1.46)
GNA11	0.198	2.12	(0.68–6.79)
SF3B1	0.409	0.56	(0.16–1.91)
EIF1AX	0.054	0.14	(0.003–1.18)
BAP1	<0.001	∞	(21.75–∞)
Chromosomal aberrations
Chromosome 1 loss	0.544	1.70	(0.44–6.95)
Chromosome 6 gain	<0.001	0.15	(0.03–0.59)
Chromosome 8 gain	<0.001	35.51	(7.60–244.70)
Genetics—gene expression profiling
Class 2 vs. class 1	<0.001	120.80	(13.65–5,905.96)

^aSignificant associations are in bold. OR, odds ratio; CI, confidence interval; N/A, not applicable.