Table 2.
Univariate and multivariate analyses of overall survival in each cohort
| Parameters | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| P-value | HR | 95% Cl | P-value | HR | 95% Cl | |||
| TCGA | ||||||||
| EIF4G1 | <0.0001*** | 2.072 | 1.359 | 3.157 | 0.00132** | 1.9974 | 1.3093 | 3.047 |
| Stage | 0.716 | 0.8072 | 0.2545 | 2.561 | 0.7005 | 0.7968 | 0.2504 | 2.535 |
| Sex | 0.39 | 0.8354 | 0.5543 | 1.259 | 0.2903 | 0.8010 | 0.5308 | 1.209 |
| Age | 0.0136* | 1.0261 | 1.005 | 1.047 | 0.02121* | 1.024 | 1.0036 | 1.045 |
| GSE21501 | ||||||||
| EIF4G1 | 0.00896** | 1.964 | 1.184 | 3.258 | 0.025* | 1.8076 | 1.077 | 3.034 |
| T stage (T1 and T2 vs T3 and T4) | 0.73 | 0.8977 | 0.4862 | 1.657 | 0.6047 | 0.8424 | 0.4400 | 1.613 |
| N stage (N0 vs N1) | 0.0425* | 1.8399 | 1.021 | 3.316 | 0.0709 | 1.7773 | 0.9523 | 3.317 |
| GSE28735 | ||||||||
| EIF4G1 | 0.045* | 2.185 | 1.018 | 4.691 | ||||
Notes: Statistically significant values are expressed in bold. *, ** and *** indicate significance at the <0.05, <0.01, and <0.001 respectively.
Abbreviation: TCGA, The Cancer Genome Atlas.