Table 2. Characteristics of the genotyped COMT SNPs.
| SNPa | Positionb | Location | Allele (minor/major) | MAF (%) | HWE p | ||
|---|---|---|---|---|---|---|---|
| Total | Male | Female | |||||
| rs737865 | 19942598 | Intron1 | C/T | 29.4 | .907 | 1.00 | .892 |
| rs5993883 | 19950115 | Intron1 | G/T | 41.1 | .841 | .675 | 1.00 |
| rs6269 | 19962429 | Exon3 | G/A | 37.8 | .182 | 1.00 | .124 |
| rs4633 | 19962712 | Exon3 | T/C | 26.4 | .105 | .795 | .089 |
| rs6267 | 19962740 | Exon3 | T/G | 7.4 | .493 | 1.00 | .408 |
| rs4818 | 19963684 | Exon4 | G/C | 37.1 | .253 | .836 | .150 |
| rs4680 | 19963748 | Exon4 | A/G | 26.7 | .062 | 1.00 | .023 |
Notes.
- HWE
- Hardy–Weinberg equilibrium
- MAF
- minor allele frequency
a
SNPs are listed down the column in sequential order from the 5′ end to the 3′ end of the sense strand of COMT.
b
Physical position is based on human genome assembly GRCh38.p12.