4. Continous outcome data: total PRBC transfusion.

Study	Reported unit	Data available	Intervention results	Control results	P value for difference between groups
Ak 2009	Units	Median (IQR)	1 (0; 1)	1 (1; 2)	0.599
Avidan 2004	mL	Median (IQR)	500 (0; 678)	495 (0; 612)	0.03
Cui 2010	Units	Median (IQR)	1 (1; 1)	1 (0.7; 1.9)	> 0.05
Girdauskas 2010	Units	Median (IQR)	6 (2; 13)	9 (4; 14)	0.20
Kempfert 2011	‐	‐	‐	‐	‐
Kultufan Turan 2006	Units	Median (IQR)	0 (0; 3)	1 (0; 2)	0.100
Nakayama 2015	mL/kg	Mean (IQR)	22 (11; 34)	30 (20; 39)	0.02
NCT00772239	‐	‐	‐	‐	‐
Nuttal 2001	Units	Median (range)	2 (0; 9)	3 (0; 70)	0.039
Paniagua 2011	mL	Mean (SD)	1774 (1394)	1604 (1366)	‐
Rauter 2007	Units	Mean	0.8	1.3	*
Royston 2001	‐	‐	‐	‐	‐
Schaden 2012	Units	Mean (SD)	3.1 (2.1)	4.8 (3.0)	0.12
Shore‐Lesserson 1999	mL	Mean (SD)	354 (487)	475 (593)	0.12
Wang 2010	Units	Mean (SD)	14.2 (7.1)	16.7 (12.8)	> 0.05
Weber 2012	Units	Median (IQR)	3 (2; 6)	5 (4; 9)	< 0.001
Westbrook 2009	Units	Total	14	33	**

*P value is reported as < 0.05, but seems to be calculated based on units given to each group instead of mean/median, thereby wrongly assuming that each of the units given are independent; **P value is reported as 0.12, but is calculated based on units given to each group instead of mean/median, thereby wrongly assuming that each of the units given are independent; ‐ indicates that data were not reported; significant result is highlighted with bold text.
 IQR: interquartile range; PRBC: pooled red blood cell; SD: standard deviation