Wang 2010.

Methods	Two‐group parallel RCT, one centre ITT: yes Funding: supported by grant from Taipei Veterans General Hospital Overall study quality: high risk of bias No sample size calculation was reported
Participants	28 adult patients undergoing orthotopic liver transplantation. No exclusion criteria stated
Interventions	Intervention group: monitored during surgery using point‐of‐care TEG analysis Control Group: monitored using standard laboratory measures of blood coagulation Specific trigger points for transfusion were established in each group with corresponding transfusion algorithms
Outcomes	Outcome measures: 3 years mortality, transfusion requirements, total amount of IV fluids (fluid total, hydroxyethyl starch, albumin), blood loss, urine output
Notes	Country: Taiwan. Language: English Letter sent to authors in November and December 2010. No reply received. Follow‐up: 3 years. No cross‐over Authors conclusion:"Thromboelastography‐guided transfusion decreases transfusion of fresh frozen plasma in patients undergoing orthotopic liver transplantation, but does not affect 3‐year survival"
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Unclear, no information provided.
Allocation concealment (selection bias)	Unclear risk	Unclear, no information provided.
Blinding (performance bias and detection bias) All outcomes	High risk	No data provided on blinding, but adequate blinding appears highly unlikely.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Appears to have adequate follow‐up.
Selective reporting (reporting bias)	Low risk	Unable to compare with protocol or trial registration but appears to be free of selective reporting.
Other bias	Low risk	Appears to be free of other types of bias.