8. Vascular occlusion methods: choice of model results.
Serious adverse events (proportion) | |||
Treatment number | Treatment name | ||
1 | Control | ||
2 | ConHVE | ||
3 | ConPTC | ||
4 | ConSelectiveHVE | ||
5 | ConSelectivePTC | ||
6 | IntPTC | ||
Fixed‐effect model | Random‐effects model | Inconsistency model | |
Dbara | 64.25 | 63.57 | 64.03 |
pDb | 12.54 | 14.37 | 14.83 |
DICc | 76.79 | 77.95 | 78.86 |
d[2]d | 0.82 (95% CrI −1.70 to 3.50) | 0.62 (95% CrI −5.00 to 5.89) | — |
d[3]e | 0.35 (95% CrI −1.26 to 1.96) | 0.16 (95% CrI −3.87 to 3.71) | — |
d[4]f | −1.98 (95% CrI −8.24 to 1.48) | −2.25 (95% CrI −9.99 to 3.38) | — |
d[5]g | −0.63 (95% CrI −2.29 to 0.97) | −1.01 (95% CrI −5.35 to 2.36) | — |
d[6]h | 0.15 (95% CrI −0.61 to 0.92) | −0.07 (95% CrI −2.53 to 1.85) | — |
Between‐study standard deviation | — | 1.216 | — |
Model used | Fixed‐effect model | ||
Evidence of inconsistency | There is no evidence of inconsistency since the difference in DIC between consistency and inconsistency models was not significant. | ||
Adverse events (proportion) | |||
Treatment number | Treatment name | ||
1 | Control | ||
2 | ConHVE | ||
3 | ConPTC | ||
4 | ConSelectiveHVE | ||
5 | ConSelectivePTC | ||
6 | IntPTC | ||
7 | IntSelectivePTC | ||
Fixed‐effect model | Random‐effects model | Inconsistency model | |
Dbara | 120.82 | 118.76 | 119.07 |
pDb | 18.10 | 21.01 | 21.93 |
DICc | 138.92 | 139.77 | 141.00 |
d[2]d | 0.95 (95% CrI −0.21 to 2.12) | 0.90 (95% CrI −1.12 to 2.84) | — |
d[3]e | 0.83 (95% CrI 0.00 to 1.69) | 0.78 (95% CrI −0.58 to 2.09) | — |
d[4]f | 0.05 (95% CrI −1.19 to 1.27) | 0.00 (95% CrI −2.05 to 1.96) | — |
d[5]g | 0.10 (95% CrI −0.81 to 1.01) | 0.07 (95% CrI −1.42 to 1.50) | — |
d[6]h | 0.24 (95% CrI −0.19 to 0.68) | 0.18 (95% CrI −0.66 to 0.88) | — |
d[7]i | 0.09 (95% CrI −0.75 to 0.93) | 0.04 (95% CrI −1.37 to 1.35) | — |
Between‐study standard deviation | — | 0.4825 | — |
Model used | Fixed‐effect model | ||
Evidence of inconsistency | There is no evidence of inconsistency since the difference in DIC between consistency and inconsistency models was not significant. | ||
Blood transfusion (proportion) | |||
Treatment number | Treatment name | ||
1 | Control | ||
2 | ConHVE | ||
3 | ConPTC | ||
4 | ConSelectiveHVE | ||
5 | ConSelectivePTC | ||
6 | IntPTC | ||
7 | IntSelectivePTC | ||
Fixed‐effect model | Random‐effects model | Inconsistency model | |
Dbara | 139.87 | 120.00 | 120.10 |
pDb | 19.04 | 25.25 | 25.72 |
DICc | 158.91 | 145.25 | 145.82 |
d[2]d | −2.55 (95% CrI −3.80 to −1.36) | −2.88 (95% CrI −7.47 to 1.47) | — |
d[3]e | −0.77 (95% CrI −1.56 to 0.01) | −1.11 (95% CrI −3.72 to 1.28) | — |
d[4]f | −1.46 (95% CrI −2.58 to −0.36) | −1.79 (95% CrI −6.38 to 2.53) | — |
d[5]g | −0.26 (95% CrI −1.18 to 0.67) | −0.48 (95% CrI −3.83 to 2.72) | — |
d[6]h | −0.34 (95% CrI −0.84 to 0.16) | −0.47 (95% CrI −2.32 to 1.28) | — |
d[7]i | −0.92 (95% CrI −1.96 to 0.08) | −0.97 (95% CrI −4.24 to 2.24) | — |
Between study standard deviation | — | 1.613 | — |
Model used | Random‐effects model | ||
Evidence of inconsistency | There is no evidence of inconsistency since the difference in DIC between consistency and inconsistency models was not significant. | ||
Blood transfusion (red blood cell) (units) | |||
Treatment number | Treatment name | ||
1 | Control | ||
2 | ConHVE | ||
3 | ConPTC | ||
4 | ConSelectiveHVE | ||
5 | ConSelectivePTC | ||
6 | IntPTC | ||
7 | IntSelectivePTC | ||
Fixed‐effect model | Random‐effects model | Inconsistency model | |
Dbara | −1.55 | −1.05 | 0.24 |
pDb | 15.99 | 17.36 | 19.34 |
DICc | 14.44 | 16.32 | 19.58 |
d[2]d | −1.65 (95% CrI −3.96 to 0.67) | −1.56 (95% CrI −4.18 to 1.14) | — |
d[3]e | −1.25 (95% CrI −2.39 to −0.10) | −1.18 (95% CrI −2.54 to 0.31) | — |
d[4]f | −2.45 (95% CrI −4.08 to −0.82) | −2.37 (95% CrI −4.33 to −0.30) | — |
d[5]g | −1.45 (95% CrI −2.59 to −0.31) | −1.41 (95% CrI −2.86 to 0.12) | — |
d[6]h | −1.36 (95% CrI −2.48 to −0.23) | −1.35 (95% CrI −2.69 to 0.01) | — |
d[7]i | −1.43 (95% CrI −2.61 to −0.24) | −1.43 (95% CrI −3.01 to 0.08) | — |
Between‐study standard deviation | — | 0.3149 | — |
Model used | Fixed‐effect model | ||
Evidence of inconsistency | There is no evidence of inconsistency since the difference in DIC between consistency and inconsistency models was not significant. | ||
Blood loss (litres) | |||
Treatment number | Treatment name | ||
1 | Control | ||
2 | ConHVE | ||
3 | ConPTC | ||
4 | ConSelectiveHVE | ||
5 | ConSelectivePTC | ||
6 | IntPTC | ||
7 | IntSelectivePTC | ||
Fixed‐effect model | Random‐effects model | Inconsistency model | |
Dbara | −45.73 | −61.66 | −63.13 |
pDb | 22.01 | 29.37 | 30.58 |
DICc | −23.72 | −32.29 | −32.55 |
d[2]d | −0.36 (95% CrI −0.50 to −0.23) | −0.37 (95% CrI −0.94 to 0.22) | — |
d[3]e | −0.02 (95% CrI −0.12 to 0.07) | −0.14 (95% CrI −0.52 to 0.14) | — |
d[4]f | −0.27 (95% CrI −0.54 to −0.01) | −0.39 (95% CrI −1.16 to 0.27) | — |
d[5]g | 0.09 (95% CrI −0.04 to 0.21) | 0.00 (95% CrI −0.57 to 0.45) | — |
d[6]h | 0.01 (95% CrI −0.05 to 0.07) | −0.06 (95% CrI −0.39 to 0.17) | — |
d[7]i | 0.00 (95% CrI −0.21 to 0.2) | −0.18 (95% CrI −0.84 to 0.30) | — |
Between‐study standard deviation | — | 0.2539 | — |
Model used | Random‐effects model | ||
Evidence of inconsistency | There is no evidence of inconsistency since the difference in DIC between consistency and inconsistency models was not significant. | ||
Con: continuous; Int: intermittent; HVE: hepatic vascular exclusion; PTC: portal triad clamping. |
aDBar = posterior mean of deviance. bpD = effective number of parameters. cDIC = deviance information criterion. dd[2] indicates effect estimate (mean difference) of treatment 2 versus treatment 1. ed[3] indicates effect estimate (mean difference) of treatment 3 versus treatment 1. fd[4] indicates effect estimate (mean difference) of treatment 4 versus treatment 1. gd[5] indicates effect estimate (mean difference) of treatment 5 versus treatment 1. hd[6] indicates effect estimate (mean difference) of treatment 6 versus treatment 1. id[7] indicates effect estimate (mean difference) of treatment 7 versus treatment 1.