Kohno 1992.

Methods	Randomised clinical trial
Participants	Country: Japan Number randomised: 62 Postrandomisation dropouts: 0 (0%) Revised sample size: 62 Average age: 62 years Women: 14 (22.6%) Number of cirrhotics: 46 (74.2%) Number of major liver resections: not stated Number of right hepatectomies: not stated Follow‐up (months): not stated Further details of methods of liver resection Vascular occlusion: not stated Parenchymal transection: not stated Fibrin glue: factor being randomised Pharmacological methods: not stated Cardiopulmonary methods: not stated Autologous transfusion: not stated Inclusion criteria: patients undergoing liver resection
Interventions	Participants were randomly assigned to 2 groups. Group 1: collagen (n = 31) Group 2: fibrin sealant (n = 31) Collagen: Avitene (Alcon Inc) Fibrin sealant: Beriplast P (Beringwerke AB)
Outcomes	The outcomes reported were: short‐term mortality, number of serious adverse events, number of adverse events, operative blood loss, and operating time.
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Comment: this information was not available.
Allocation concealment (selection bias)	Unclear risk	Comment: this information was not available.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Comment: this information was not available.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Comment: this information was not available.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Comment: there were no postrandomisation dropouts.
Selective reporting (reporting bias)	Low risk	Comment: mortality and morbidity were reported.
Vested interest bias	Unclear risk	Comment: this information was not available.
Other bias	Low risk	Comment: no other bias