Kostopanagiotou 2007.
Methods | Randomised clinical trial | |
Participants | Country: Greece
Number randomised: 35
Postrandomisation dropouts: 7 (20%)
Revised sample size: 28
Average age: 52 years
Women: 11 (39.3%)
Number of cirrhotics: 0 (0%)
Number of major liver resections: 16 (57.1%)
Number of right hepatectomies: 11 (39.3%)
Follow‐up (months): 12
Further details of methods of liver resection
Inclusion criteria
Exclusion criteria: receiving immunosuppressive drugs |
|
Interventions | Participants were randomly assigned to 2 groups. Group 1: autologous blood donation (n = 15) Group 2: control (n = 13) Autologous blood donation: 2 units of blood were withdrawn before surgery | |
Outcomes | The outcomes reported were: short‐term mortality, long‐term mortality, proportion of people with any adverse events, operative blood loss, quantity of blood transfused (red cell transfusion or whole blood), length of hospital stay, and operating time. | |
Notes | Reasons for postrandomisation dropouts: requirement of allogenic transfusion in autologous group or did not require any transfusion (4 in intervention group and 3 in control group) | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: this information was not available. |
Allocation concealment (selection bias) | Unclear risk | Comment: this information was not available. |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: this information was not available. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: this information was not available. |
Incomplete outcome data (attrition bias) All outcomes | High risk | Comment: there were postrandomisation dropouts. |
Selective reporting (reporting bias) | High risk | Comment: severity of morbidity was not reported. |
Vested interest bias | Unclear risk | Comment: this information was not available. |
Other bias | Low risk | Comment: no other bias |