Park 2012.

Methods	Randomised clinical trial
Participants	Country: South Korea Number randomised: 53 Postrandomisation dropouts: 3 (5.7%) Revised sample size: 50 Average age: 31 years Women: 11 (22%) Number of cirrhotics: 0 (0%) Number of major liver resections: 50 (100%) Number of right hepatectomies: 50 (100%) Follow‐up (months): until discharge Further details of methods of liver resection Vascular occlusion: factor being randomised Parenchymal transection: not stated Fibrin glue: not stated Pharmacological methods: not stated Cardiopulmonary methods: not stated Autologous transfusion: not stated Inclusion criteria: donors underwent right hemihepatectomy and recipients received right hemiliver grafts Exclusion criteria Recipient had experienced fulminant hepatic failure The graft‐to‐recipient body weight ratio (GRWR) was < 0.9% A frozen biopsy sample from the donor liver showed > 30% macrovesicular steatosis before donor hemihepatectomy The transplant was ABO‐incompatible The recipient had previously undergone organ transplantation The recipient had undergone or was scheduled to undergo multiorgan transplantation
Interventions	Participants were randomly assigned to 2 groups. Group 1: intermittent portal triad clamping (n = 25) Group 2: control (n = 25) Intermittent portal triad clamping: 15 min on and 5 min off
Outcomes	The outcomes reported were: proportion of people with serious adverse events, operative blood loss, length of hospital stay, and operating time.
Notes	Reasons for postrandomisation dropouts: graft‐to‐recipent body weight ratio < 0.9%
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "The donor‐recipient pairs were randomized (1:1) into 2 groups (IHIO and control groups) at the time of anesthesia induction for donors via the extraction of a black or white (but otherwise identical) stone from an unseen box". Comment: IHIO: intermittent hepatic inflow occlusion
Allocation concealment (selection bias)	Low risk	Quote: "The donor‐recipient pairs were randomized (1:1) into 2 groups (IHIO and control groups) at the time of anesthesia induction for donors via the extraction of a black or white (but otherwise identical) stone from an unseen box".
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Comment: this information was not available.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Comment: this information was not available.
Incomplete outcome data (attrition bias) All outcomes	High risk	Comment: there were postrandomisation dropouts.
Selective reporting (reporting bias)	High risk	Comment: mortality and morbidity were not reported adequately.
Vested interest bias	Low risk	Quote: "This study was funded by the Clinical Research Development Program (CRS1091811)".
Other bias	Low risk	Comment: no other bias