Akhlaghi 2008.
Methods | RCT in 1 hospital, Mashhad Zeinab, Iran. | |
Participants | 400 women, elective CS. No information on anaesthesia or parity or previous CS. Mean age: 27.3 years in intervention group and 26.6 years in control group. Exclusion criteria: complications during or after surgery. |
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Interventions |
Intervention group (N = 200): chewed sugar‐free and flavourless gum after regaining consciousness after surgery, for 45 min per session, 3 times/d at 8:00, 14:00 and 20:00 (total 135 min/d), until the regular diet was initiated. Control group (N = 200): routine care which consisted of "restriction of oral intake until the bowel function was returned" (conventional feeding). |
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Outcomes | Time of the first flatus passage, bowel sound*, defecation, duration of hospital stay and gum tolerability. Additional outcomes: time to ambulation post CS and to initiation regular diet. |
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Notes | *Time to bowel sounds not included in meta‐analysis because there was only mean value and no information on standard deviation. We wrote to authors but obtained no response. No study protocol available. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No information available. |
Allocation concealment (selection bias) | Unclear risk | No information available. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | "The nature of the study did not allow blinding after application of the assigned intervention." |
Blinding of outcome assessment (detection bias) Subjective outcomes | High risk | Participants were unable to be adequately blinded in relation to passage of flatus and stools or tolerability to gum. |
Blinding of outcome assessment (detection bias) Objective outcomes | Unclear risk | No information on blinding of outcome assessors for hearing of bowel sounds and length of hospital stay, ileus or use of antiemetics or analgesics NA. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No losses. |
Selective reporting (reporting bias) | Low risk | All pre‐specified outcomes in Methods were reported in Results. |
Other bias | Unclear risk | No information. |