Marshall‐UK 1995.
Methods | Allocation: randomised. Design: single centre. Duration: 14 months. Country: Oxford, UK. | |
Participants | Diagnosis*: severe persistent psychiatric disorder. N = 80. Setting: Oxford Social Service. Age: 20 to over 60 years, mean ˜ 48 years. Sex: 85% M (68M, 12F). Ethnicity: not reported. History**: i. either homeless, at risk of homelessness, living in supported, temporary or poor‐quality accommodation, experiencing social isolation, or causing disturbances, ii. not already receiving case management, iii. informed consent given. | |
Interventions | 1. ICM: Case Management from team of social services case managers (case managers are free to choose how much time to offer each patient, but at minimum provided some intervention). Caseload: ˜ 1:10. N = 40. 2. Standard care: provided by CMHTs. N = 40. | |
Outcomes | Service use: average number of days in hospital per month, admitted to hospital.
Death: all causes.
Global state: leaving the study early.
Social functioning: REHAB scale, imprisonment, employment.
Quality of life: Quality of Life Index.
Costs: costs of all care per week (including accomodation). Unable to use ‐ Need for care: Medical Research Council (MRC) Needs for Care Schedule (version modified by authors). Behaviour: Social Integration Questionnaire (not published in peer‐reviewed journal). Social functioning: accomodation status (the definition of "better" and "worse" accommodation status was not clearly stated), employment (no mean and SD reported). Costs: direct cost of psychiatric hospital care and of health care (no SD). |
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Notes | *Schizophrenia and related disorder 74%. **40% illness > 1 yr, 85% previous psychiatric admission. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomisation by permuted block. No further details. |
Allocation concealment (selection bias) | Unclear risk | Randomisation by sealed envelopes (not stated if opaque). |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Primary outcome: clinician/participant mediated ‐ rating ‐ Unclear. Secondary outcomes: those interviewer rated ‐ rating ‐ Unclear. No details. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Problematic to blind participants and those providing the intervention in studies comparing ICM intervention with standard care. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Data for service use (hospitalisation), costs, social functioning (employment; accomodation), non‐psychiatric health care, psychiatric health care provided by the respective healthcare providers. Blinding not reported. Mental state and social functioning (social behaviour measured by REHAB) rated by a trained observer. Blinding not reported. Social functioning and quality of life self reported. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Insufficient reporting of attrition/exclusion (no reasons for missing data provided). Lost to follow‐up reported at 7 months, not at 14 months. Reasons for attrition reported only for the experimental sample. |
Selective reporting (reporting bias) | Low risk | Listed outcomes reported completely. |
Other bias | Low risk | No details. No evidence of the presence of other bias. |