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. 2019 Apr 18;14(4):e0214763. doi: 10.1371/journal.pone.0214763

Fig 3. Biocidal effect of 10-undecynoic acid against the pre-existing biofilm of Streptococcus mutans UA159 and Streptococcus sobrinus SL1.

Fig 3

(A-C) MBBC values were determined on 96-well plates coated with human saliva up to 24 h incubation period with 10-undecynoic acid and assessed by BHI agar plating method after 24 h and alamarBlue after 16 h of recovery period. (D) Representative images of Streptococcus mutans UA159 and Streptococcus sobrinus SL1 after 24 h incubation period with 5.0 mg/ml of 10-undecynoic acid stained with SYTO9/PI. Green fluorescence–live biofilm, red fluorescence–dead biofilm, control– 0.1% DMSO, 10-UDYA– 10-undecynoic acid, # p<0.05, * p<0.001 compared to control.