Table 4. Validity and reliability of global status measures used in treatment efficacy studies in Alzheimer’s Dementia (n = 9).
| Name of Scale | Validity | Reliability | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Face/Content | Construct | Criterion | Concurrent | Predictive | Convergent | Discriminant | Internal consistency | Test-retest | Inter-rater | |
| ADCS-CGI (1997)[92] | ✓ | ✓ | ✓ | |||||||
| CRGI (1994)[90] | ✓ | |||||||||
| CGIC (1996)[23, 91] | ✓ | ✓ | ||||||||
| CGIC-severe (1992)[91, 93] | ✓ | ✓ | ✓ | |||||||
| CGI-I (2006)[91] | ✓ | ✓ | ✓ | |||||||
| CIBIC- plus (1994)[22, 90] | ✓ | ✓ | ||||||||
| CSS (1990)[94, 95] | ✓ | ✓ | ✓ | |||||||
| GBS (1982)[96, 97] | ✓ | ✓ | ✓ | |||||||
| SCB (1991)[98] | ✓ | ✓ | ✓ | ✓ | ||||||
Abbreviation: ADCS-CGIC Alzheimer’s Disease Cooperative Studies–Clinician Global Impressions of Change; CSS Caregiver Stress Scale; CRGI Caregiver-rated Global Impression; CGIC-severe Clinical Global Impression of Change—severe subscale; CGIC Clinical Global Impression of Change; CGI-I Clinical Global Impression of Improvement; CIBIC-plus Clinician Interview-Based Impression of Change plus caregiver input; GBS Gottfries-Bråne-Steen Scale, SCB Screen for Caregiver Burden. Note Year reported is based on the earliest published paper reporting on validity or reliability for each outcome measure. Patient Global Assessment (PGA) scale could not be located