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. 2019 Apr 18;14(4):e0215443. doi: 10.1371/journal.pone.0215443

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© 2019 Broger et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — The two plots compare the LAM and ESAT-6 concentrations in urine (panel a) and serum (panel b). The plots display the LAM concentration measured with the most sensitive LAM capture antibody for each matrix: S4-20 for urine and FIND 28 for serum. Concentrations in serum are corrected for the additional 4-fold dilution of serum samples relative to urine samples. The dashed orange lines show the dilution-corrected detection limits for the assays. Data points with signals below the detection thresholds (categorized as “ND” or not detectable) are shown for completeness, but do not have assigned concentrations (see, the discussion in the Fig 3 legend). Percentages of categorical agreement are shown in S5 Table. Data points are colored based on TB status and filled based on HIV status as indicated in the key.