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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Photochem Photobiol. 2018 Nov 26;95(1):430–438. doi: 10.1111/php.13040

Figure 1. PDT induces tumor-localized luminol chemiluminescence.

Figure 1.

Murine mesothelioma flank tumors (AB12) were treated with PDT and imaged for inflammation via intraperitoneal injection of luminol (300 mg/kg). Images were captured prior to light delivery for PDT and at 1 and 4 hours after the initiation of light delivery for PDT. PDT-generated chemiluminescence increased transiently at 1h with a subsequent decrease at 4h (p = 0.008 for 1h vs 4 hr). Signal at both the 1h and 4h timepoints after PDT was significantly greater than baseline (*p = 0.0011 at 1h, 0.008 for 4h). Solid square symbol at 1h timepoint indicates outlier. N = 15