Table 1.
Characteristics of H. pylori strains examined in this study
| ClaS-ClaR strain pairs | Isolated from | MIC, μg/ml
|
23S rRNA mutation | |||||
|---|---|---|---|---|---|---|---|---|
| Amo | Met | Tet | Cef | Cip | Cla | |||
| 67:21 | Peptic ulcer | <0.016 | ND | ND | ND | ND | <0.016 | Wt |
| 67:21 ClaR | In vitro | <0.016 | ND | ND | ND | ND | 8 | A2143 → G |
| G6 | Peptic ulcer | <0.016 | 0.38 | 0.094 | 0.19 | 0.094 | <0.016 | Wt |
| G44 | Peptic ulcer | <0.016 | 0.125 | 0.047 | 0.5 | 0.047 | 8 | A2143 → G |
| G47 | Non-ulcer dyspepsia | <0.016 | 0.032 | 0.047 | 0.25 | 0.032 | <0.016 | Wt |
| G108 | Non-ulcer dyspepsia | <0.016 | ND | ND | ND | ND | 8 | A2143 → G |
| G142 | Non-ulcer dyspepsia | <0.016 | 0.125 | 0.064 | 0.5 | 0.047 | <0.016 | Wt |
| G193 | Non-ulcer dyspepsia | <0.016 | 0.047 | 0.047 | 0.38 | 0.047 | 8 | A2143 → G |
| G34 | Peptic ulcer | <0.016 | 0.094 | 0.19 | 0.38 | 0.047 | <0.016 | Wt |
| G49 | Peptic ulcer | <0.016 | 0.094 | 0.064 | 0.5 | 0.047 | >256 | A2142 → G |
| G83 | Non-ulcer dyspepsia | <0.016 | 64 | 0.064 | 0.38 | 0.064 | <0.016 | Wt |
| G162 | Non-ulcer dyspepsia | <0.016 | 0.5 | 0.023 | 1.0 | 0.094 | >256 | A2142 → G |
| G16 | Non-ulcer dyspepsia | <0.016 | ND | ND | ND | ND | <0.016 | Wt |
| G33 | Peptic ulcer | <0.016 | >256 | 0.064 | 0.75 | 0.125 | <0.016 | Wt |
| G36 | Peptic ulcer | <0.016 | 0.023 | 0.047 | 0.25 | 0.032 | <0.016 | Wt |
| G54 | Non-ulcer dyspepsia | <0.016 | >256 | 0.032 | 0.064 | 0.047 | <0.016 | Wt |
| G59 | Non-ulcer dyspepsia | <0.016 | 0.023 | 0.023 | 0.125 | 0.032 | <0.016 | Wt |
| G64 | Non-ulcer dyspepsia | <0.016 | 0.125 | 0.023 | 0.047 | 0.023 | <0.016 | Wt |
| G66 | Peptic ulcer | <0.016 | <0.016 | <0.016 | 0.25 | 0.023 | <0.016 | Wt |
| G67 | Non-ulcer dyspepsia | <0.016 | 0.047 | 0.094 | 0.25 | 0.032 | <0.016 | Wt |
| G74 | Peptic ulcer | <0.016 | 0.125 | 0.032 | 0.19 | 0.032 | <0.016 | Wt |
| G76 | Peptic ulcer | <0.016 | 0.19 | 0.094 | 0.5 | 0.125 | <0.016 | Wt |
| G77 | Peptic ulcer | <0.016 | 0.25 | 0.094 | 0.25 | 0.047 | <0.016 | Wt |
| G84 | Non-ulcer dyspepsia | <0.016 | 0.19 | 0.094 | 0.5 | >32 | <0.016 | Wt |
| G86 | Non-ulcer dyspepsia | <0.016 | 0.19 | 0.064 | 0.25 | 0.032 | <0.016 | Wt |
| G88 | Peptic ulcer | <0.016 | <0.016 | 0.023 | 0.19 | 0.032 | <0.016 | Wt |
| G90 | Non-ulcer dyspepsia | <0.016 | 0.032 | 0.047 | 0.5 | 0.064 | <0.016 | Wt |
| G117 | Non-ulcer dyspepsia | <0.016 | ND | ND | ND | ND | <0.016 | Wt |
| K65 | Peptic ulcer | ND | ND | ND | ND | ND | <0.016 | Wt |
| K57 | Gastric cancer | <0.016 | <0.016 | <0.016 | 0.047 | 0.023 | <0.016 | Wt |
| K59 | Gastric cancer | <0.016 | <0.016 | <0.016 | 0.47 | 0.0047 | <0.016 | Wt |
| K66 | Gastric cancer | ND | ND | ND | ND | ND | <0.016 | Wt |
| 26695 | Gastritis | ND | ND | ND | ND | ND | <0.016 | Wt |
MIC, minimal inhibitory concentration; Cla, clarithromycin; Met, metronidazole; Tet, tetracycline; Amo, amoxicillin; Cip, ciprofloxacine; Cef, ceftazidime; ND, not determined; Wt, wild type.