Table 1.
ASD (N = 78) | DD (N = 45) | GP (N = 149) | Autism versus GP p valuea | Autism versus DD p valuea | ||||
---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | |||
Child’s sex | 0.664b | 0.001b | ||||||
Male | 68 | 87.18 | 27 | 60 | 133 | 89.26 | ||
Female | 10 | 12.82 | 18 | 40 | 16 | 10.74 | ||
Birth year | 0.248b | 0.019b | ||||||
2000 | 22 | 28.21 | 23 | 51.11 | 31 | 20.81 | ||
2001 | 56 | 71.79 | 22 | 48.89 | 118 | 79.19 | ||
Plurality | 0.416b | 1b | ||||||
Singleton | 75 | 96.15 | 43 | 95.56 | 146 | 97.99 | ||
Multiple | 3 | 3.85 | 2 | 4.44 | 3 | 2.01 | ||
Mother’s race | 0.074 | 0.771 | ||||||
White | 51 | 67.11 | 33 | 73.33 | 118 | 79.19 | ||
Asian | 19 | 25 | 9 | 20 | 27 | 18.12 | ||
Other | 6 | 7.89 | 3 | 6.67 | 4 | 2.68 | ||
Mother’s ethnicity | 0.001 | <0.001 | ||||||
Non-Hispanic | 60 | 76.92 | 19 | 42.22 | 80 | 53.69 | ||
Hispanic | 18 | 23.08 | 26 | 57.78 | 69 | 46.31 | ||
Maternal birth Country | <0.001 | <0.001 | ||||||
US | 41 | 52.56 | 12 | 26.67 | 63 | 42.28 | ||
Mexico | 8 | 10.26 | 22 | 48.89 | 57 | 38.26 | ||
Other | 29 | 37.18 | 11 | 24.44 | 29 | 19.46 | ||
Maternal age (years) mean (SD) | 30.7 (5.3) | 28.5 (5.1) | 28.3 (5.6) | 0.0016 | 0.0285 | |||
Maternal age (years) | 0.027 | 0.146 | ||||||
<20 | 2 | 2.56 | 3 | 6.67 | 8 | 5.37 | ||
20–24 | 7 | 8.97 | 6 | 13.33 | 31 | 20.81 | ||
25–29 | 18 | 23.08 | 17 | 37.78 | 44 | 29.53 | ||
30–34 | 34 | 43.59 | 14 | 31.11 | 48 | 32.21 | ||
35+ | 17 | 21.79 | 5 | 11.11 | 18 | 12.08 | ||
Maternal weight prior to XAFP blood draw (lbs) mean (SD) | 143.6 (26.4) | 147.3 (35.3) | 144.6 (27.2) | 0.7997 | 0.5186 | |||
Gestational age at XAFP blood draw (days) mean (SD) | 119.9 (8.2) | 118.8 (8.7) | 118.8 (7.4) | 0.3057 | 0.4962 | |||
Gestational age at birth (days) mean (SD) | 271.0 (14.5) | 265.2 (29.0) | 271.7 (19.0) | 0.753 | 0.1385 | |||
Gestational age at birth (weeks) | 0.849 | 0.239 | ||||||
<33 | 2 | 2.56 | 4 | 9.09 | 4 | 2.68 | ||
33 to <37 | 7 | 8.97 | 5 | 11.36 | 17 | 11.41 | ||
≥37 | 69 | 88.46 | 35 | 79.55 | 128 | 85.91 |
t test for means, Chi squared for frequencies (of non-missing/unknown categories), excluding missing data
Fisher’s exact test, excluding missing data