Comparison 1. Mitomycin C versus placebo during aqueous shunt surgery.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Mean intraocular pressure at 4 weeks	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
2 Mean intraocular pressure at 12 weeks	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
3 Mean intraocular pressure at 6 months	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4 Mean intraocular pressure at 12 months	3	78	Mean Difference (IV, Fixed, 95% CI)	0.12 [‐2.16, 2.41]
5 Mean number of antiglaucoma medications at 12 months	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
6 Proportion of participants with adverse event	2		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
6.1 Choroidal effusion	2		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6.2 Corneal edema	2		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6.3 Flat anterior chamber	2		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6.4 Retinal detachment	2		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]