Fig 6.
Effect of cell size on peptide uptake efficiency. HeLa cells (average cross-sectional area of 500 μm2) and OPM-2 cells (average cross-sectional area 90 μm2) were incubated with 50 μM ARG for 60 minutes at 37 °C. (a) The mean fluorescence intensity for the entire population of cells was compared for HeLa (n=97 cells) and OPM2 (n=26 cells). *denotes p<0.00001 (b) The mean fluorescent intensity values for the entire population of cells was divided by the average cellular cross-sectional area for both HeLa and OPM2 cells to calculate the fluorescence density. **denotes p>0.05.