TABLE 2.
Associations between demographic characteristics and malignant melanoma incidence rates among children and adolescents, 1995-2013
| Texas |
SEER 13 |
|||||||
|---|---|---|---|---|---|---|---|---|
| Characteristic | Univariable IRR (95% CI) | p-value | Multivariable Adjusted IRRa (95% CI) | p-value | Univariable IRR (95% CI) | p-value | Multivariable Adjusted IRRa (95% CI) | p-value |
| Sex | ||||||||
| Male | Reference | -- | Reference | -- | Reference | -- | Reference | -- |
| Female | 1.26 (1.05, 1.52) | 0.012 | 1.33 (1.12, 1.57) | 0.001 | 1.65 (1.44, 1.90) | <0.001 | 1.59 (1.42, 1.80) | <0.001 |
| Age at diagnosis, years | ||||||||
| 0-4 | Reference | -- | Reference | -- | Reference | -- | Reference | -- |
| 5-9 | 1.21 (0.77, 1.91) | 0.411 | 1.18 (0.76, 1.86) | 0.459 | 1.64 (1.08, 2.50) | 0.021 | 1.58 (1.05, 2.37) | 0.029 |
| 10-14 | 2.73 (1.82, 4.08) | <0.001 | 2.49 (1.68, 3.70) | <0.001 | 4.09 (2.79, 6.01) | <0.001 | 3.51 (2.43, 5.08) | <0.001 |
| 15-20 | 11.19 (7.83, 15.98) | <0.001 | 10.25 (7.23, 14.54) | <0.001 | 24.73 (17.49, 34.98) | <0.001 | 19.79 (14.14, 27.72) | <0.001 |
| Race/ethnicity | ||||||||
| Other | Reference | -- | Reference | -- | Reference | -- | Reference | -- |
| Hispanic | 2.01 (1.21, 3.34) | 0.007 | 2.17 (1.30, 3.61) | 0.003 | 2.81 (1.90, 4.14) | <0.001 | 2.88 (1.97, 4.21) | <0.001 |
| Non-Hispanic White | 16.62 (10.46, 26.40) | <0.001 | 16.82 (10.61, 26.65) | <0.001 | 19.12 (14.03, 26.06) | <0.001 | 18.10 (13.22, 24.77) | <0.001 |
| County-level povertyb | ||||||||
| High | Reference | -- | Reference | -- | Reference | -- | Reference | -- |
| Low | 1.48 (1.22, 1.80) | <0.001 | 1.22 (1.02, 1.46) | 0.030 | 1.80 (1.46, 2.22) | <0.001 | 1.17 (1.00, 1.37) | 0.049 |
| Year of diagnosisc | ||||||||
| 1995-1998 | Reference | -- | Reference | -- | Reference | -- | Reference | -- |
| 1999-2002 | 1.41 (1.05, 1.91) | 0.024 | 1.42 (1.07, 1.87) | 0.014 | 1.38 (1.11, 1.71) | 0.004 | 1.32 (1.09, 1.59) | 0.004 |
| 2003-2006 | 1.94 (1.46, 2.58) | <0.001 | 1.92 (1.48, 2.50) | <0.001 | 1.51 (1.22, 1.86) | <0.001 | 1.52 (1.27, 1.81) | <0.001 |
| 2007-2010 | 1.58 (1.16, 2.14) | 0.004 | 1.52 (1.13, 2.04) | 0.005 | 1.22 (0.98, 1.52) | 0.078 | 1.15 (0.95, 1.39) | 0.148 |
| 2011-2013 | 1.12 (0.80, 1.57) | 0.521 | 1.11 (0.81, 1.54) | 0.514 | 1.15 (0.91, 1.46) | 0.245 | 1.08 (0.88, 1.33) | 0.448 |
Abbreviations: CI, confidence interval; IRR, incidence rate ratio
a
Adjusted IRRs are mutually adjusted for all variables listed in the table.
b
Four-year increments, except for 2011-2013 which is a three-year increment.
c
Low county-level poverty category includes those living in a county with ≤15% of households below the poverty level; High county-level poverty category includes those living in a county with >15% of households below the poverty level.