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Eighty-three-year-old woman with primary ER-positive/HER2-negative invasive ductal breast carcinoma. a89Zr-trastuzumab maximum intensity projection demonstrates several foci of 89Zr-trastuzumab avidity that localize to osseous structures. b Axial CT and 89Zr-trastuzumab PET/CT demonstrate 89Zr-trastuzumab avidity in proximal left femur. Reprinted with permission from ref. [49]. Copyright 2016 Society of Nuclear Medicine
