Table 3.
Year | mAb | Target | Tumor type | Refs. |
---|---|---|---|---|
2006 | Chimeric mAb U36 | CD44v6 | Head and neck cancer | [37] |
2012 | Ibritumomab-tiuxetan | CD20 | B cell lymphoma | [38] |
2013 | Bevacizumab | VEGF-A | Breast cancer | [39] |
2014 | Bevacizumab | VEGF-A | Neuroendocrine tumors | [40] |
2015 | Fresolimumab | TGF-β | Glioma | [41] |
2016 | MMOT0530A | MSLN | Pancreatic, ovarian cancer | [42] |
2017 | Cetuximab | EGFR | Head and neck, lung cancer | [43] |
2017 | Rituximab | CD20 | B cell lymphoma | [44] |
2017 | Lumretuzumab | HER3 | Multiple cancer types | [45] |
2017 | Bevacizumab | VEGF-A | Metastatic renal cell carcinoma | [46] |
2018 | Trastuzumab | HER2 | Breast cancer | [47] |
2018 | Atezolizumab | PD-L1 | Bladder cancer, non-small cell lung cancer, triple-negative breast cancer | [48] |