Table 2.
Univariate regression analysis.
| NIHSS (n = 321) | Favorable functional outcome (n = 289) | |||
|---|---|---|---|---|
| Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | |
| DEMOGRAPHIC VARIABLES | ||||
| Age, years | 0.3% (−0.5 to 1.1%) | 0.416 | 0.93 (0.91 to 0.96) | < 0.001 |
| Sex, men | 11.1% (−18.6 to 22.8%) | 0.996 | 1.90 (1.06 to 3.41) | 0.030 |
| Hypertension | −7.2% (−26 to 16.3%) | 0.516 | 0.33 (0.14 to 0.70) | 0.007 |
| Diabetes | 28.4% (3.6 to 59.1%) | 0.023 | 0.62 (0.34 to 1.12) | 0.109 |
| Dyslipidemia | 6.9% (−18 to 39.5%) | 0.621 | 1.39 (0.64 to 3.36) | 0.431 |
| Metabolic syndrome | 4.2% (−14.8 to 27.3%) | 0.689 | 0.68 (0.37 to 1.21) | 0.188 |
| Body mass index, kg/m2 | −2% (−4.8 to 0.9%) | 0.174 | 1.06 (0.98 to 1.16) | 0.162 |
| Smoker | 21.9% (−3.5 to 53.8%) | 0.097 | 1.80 (0.89 to 3.96) | 0.120 |
| Atrial fibrillation | 32.6% (2 to 72.3%) | 0.036 | 0.51 (0.26 to 1.04) | 0.057 |
| Ischemic heart disease | −69.2% (−75 to −62.1%) | 0.093 | 1.50 (0.82 to 2.82) | 0.198 |
| Peripheral artery occlusive disease | 45.5% (1.5 to 108.6%) | 0.042 | 0.47 (0.19 to 1.29) | 0.122 |
| STROKE VARIABLES | ||||
| NIHSS at admission | 0.83 (0.77 to 0.88) | < 0.001 | ||
| Duration of hospitalization (days) | 0.79 (0.73 to 0.86) | < 0.001 | ||
| LABORATORY VARIABLES | ||||
| Aspartate aminotransferase, μkat/L | −24.7% (−51.7 to 17.3%) | 0.210 | 0.60 (0.19 to 2.15) | 0.399 |
| Alanine aminotransferase, μkat/L | −25.6% (−44.5 to −0.3%) | 0.048 | 2.49 (0.86 to 11.18) | 0.163 |
| Platelet count, × 103/mm3 | 0% (−0.1 to 0.1%) | 0.819 | 1.00 (1.00 to 1.00) | 0.725 |
| Fasting blood glucose, mmol/L | 4.7% (1.3 to 8.3%) | 0.007 | 0.95 (0.86 to 1.04) | 0.212 |
| eGFR, | 0.2% (−0.4 to 0.8%) | 0.538 | 1.01 (0.99 to 1.02) | 0.432 |
| Total cholesterol, mmol/L | 7.7% (−1.5 to 17.8%) | 0.102 | 0.97 (0.75 to 1.26) | 0.804 |
| Triglyceride, mmol/L | −0.2% (−9.8 to 10.4%) | 0.968 | 1.40 (0.96 to 2.24) | 0.127 |
| High-density lipoprotein, mmol/L | −6.1% (−33.6 to 32.7%) | 0.721 | 1.02 (0.39 to 2.85) | 0.967 |
| Low-density lipoprotein, mmol/L | 12.3% (1.2 to 24.7%) | 0.030 | 0.89 (0.66 to 1.21) | 0.443 |
| LIVER VARIABLES | ||||
| Liver stiffness, kPa | 1.6% (−1 to 4.2%) | 0.236 | 0.96 (0.89 to 1.02) | 0.159 |
| Advanced fibrosis, >8 kPa | 5.6% (−24.5 to 47.8%) | 0.750 | 0.77 (0.32 to 2.03) | 0.565 |
| CAP, dB/m | −0.3% (−0.5 to 0%) | 0.022 | 1.01 (1.01 to 1.02) | < 0.001 |
| NAFLD, >220dB/m | −24.9% (−39.8 to −6.3%) | 0.012 | 2.44 (1.36 to 4.40) | 0.003 |
NIHSS, National Institute of Health Stroke Scale; eGFR, estimated glomerular filtration rate; CAP, controlled attenuation parameter; NAFLD, non-alcoholic fatty liver disease. Data are given as hazard ratio (95% confidence interval).