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. 2019 Apr 12;13:356. doi: 10.3389/fnins.2019.00356

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Copyright © 2019 Colmenárez-Raga, Díaz, Pernia, Pérez-González, Delgado-García, Carro, Plaza and Merchán.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GFAP immunocytochemistry of coronal sections of multisession-stimulated and sham-operated rat brains. (A) Panoramic view of a case of the multisession protocol group, which shows a restricted cortical intramural increase in immunoreactivity where the stimulation electrode is located (on the AC). (B,C) Sham-operated control showing a small, dense immunoreactive area in the surface and a restricted, superficial band devoid of labeling. (D,E) Active zone (AZ) of electric stimulation. Note the intense staining of astrocytes and blood vessels inside AZ.