FIGURE 3.

Inhibition of ZIKV Paraiba/2015 infection by ATA: Vero (A,C) or A549 (B,D) cells (96-well plate format, 5 × 10⁴ cells/well, triplicates) were infected with 25 PFU of Paraiba/2015. After 1 h of viral adsorption, the indicated concentrations (twofolds dilutions, starting concentration 1,000 μM) of ATA (A,B) or ARB (C,D) were added to 100 μl of infection media containing 1% Avicel. At 36 h p.i., infected cells were fixed for virus titration by immunostaining assay. Dotted line indicates 50% inhibition. Data was expressed as mean and SD from three independent experiments conducted in triplicates.