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. 2019 Apr 12;10:757. doi: 10.3389/fimmu.2019.00757

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Copyright © 2019 Liubomirski, Lerrer, Meshel, Rubinstein-Achiasaf, Morein, Wiemann, Körner and Ben-Baruch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In basal patients, the expression levels of the pro-inflammatory cytokines TNFα and IL-1β are significantly coordinated with the expression levels of their chemokine targets. The Figure demonstrates correlation analyses of gene expression in basal patients, performed with the TCGA breast cancer dataset. (A) CXCL8 correlations with TNFα (A1) and IL-1β (A2). (B) CCL2 correlations with TNFα (B1) and IL-1β (B2). (C) CCL5 correlations with TNFα (C1) and IL-1β (C2). RSEM, RNAseq by expectation-maximization.