Figure 7.

CXCL8 expression is down-regulated in TNFα- and IL-1β-stimulated luminal-A (MCF-7): MSC “Contact” co-cultures. The Figure demonstrates similar experiments and statistical analyses as those of Figure 3, performed herein with MCF-7 cells and MSCs. Cytokine concentrations: 50 ng/ml TNFα and 500 pg/ml IL-1β. (A) Activation of p65 and JNK. (B) CXCL8 expression levels. In all parts of the Figure, the results are of a representative experiment of n≥3 independent experiments, performed with MSCs of 2 different donors. *, **, ***, # - As described in Figure 3.