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. 2019 Apr 12;7:53. doi: 10.3389/fcell.2019.00053

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Copyright © 2019 Tucker and Degen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Described functions of tenascin-W (TNW). As a matricellular protein, TNW regulates the interplay between stromal and epithelial cells, and between cells and other extracellular matrix (ECM) components, thereby influencing cancer cell behavior and promoting tumor formation.