Date	Event	Description
23 November 2016	Amended	Author contact details updated.
19 September 2016	New citation required but conclusions have not changed	One small randomised controlled trial (Sun 2015) included with only toxicity outcomes. An additional 17 trials excluded. Conclusions remain unchanged.
19 September 2016	New search has been performed	Literature searches updated 8 September 2016.
16 May 2012	Amended	Author listing amended
25 April 2012	New citation required but conclusions have not changed	Review updated: Twelve records screened: one study was added to 'excluded studies' (Zola 2003) and three studies added to 'ongoing studies' (Hong 2013; GOG 0263; NCT 00806117). Conclusions unchanged.
8 November 2011	New search has been performed	Search updated (MEDLINE, EMBASE, CENTRAL, LILACS and SR) rendering 1,197 records (1,031 records after de‐duplication, plus three ongoing studies).