Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 14;51(2):797–811. doi: 10.4143/crt.2018.364

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 by the Korean Cancer Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 8. — Human interferon β from HB1.F3.CD.IFN-β cell line prevented epithelial-mesenchymal transition (EMT) and metastasis in melanoma cell line (A375SM). To confirm the effect of recombinant interferon-β of HB1.F3.CD.IFN-β on EMT and metastasis, the melanoma cell line (A375SM) was cultured with conditioned media from HB1.F3.CD.IFN-β for 0, 24, 48, and 72 hours. Expressions of epithelial protein E-cadherin, mesenchymal protein Slug, and metastasis protein cathepsin-B were measured by western blot. (A) The melanoma cell line was cultured with conditioned media from the HB1.F3.CD cell line as a control. (B) The melanoma cell line was cultured with conditioned media from HB1.F3.CD.IFN-β cell line. Data are displayed as the mean±standard deviation of three distinct experiments each conducted in triplicate. *p < 0.05 vs. 0 hour. GAPDH, glyceraldehyde 3-phosphate dehydrogenase.