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. 2019 Apr 12;9:265. doi: 10.3389/fonc.2019.00265

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Copyright © 2019 Weinberger, Bednarikova, Hausnerova, Ovesna, Vinklerova, Minar, Felsinger, Jandakova, Cihalova and Zikan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Patients with L1CAM positivity >4% were identified as high risk; in fact 86% of them were high-risk indeed. Patients with L1CAM value from 1 to 4% were further divided according to myometrial invasion. In case of myometrial invasion <50% they were stratified as low-risk, on the contrary in case of myometrial invasion >50% or unknown they were classified as high-risk. Patients with L1CAM <1% were further disaggregated by PR value. In case of PR >85% they were identified as low-risk (with success rate of 100%), on the other hand in case of PR ≤85% they were stratified as high-risk according to clinical preference for more precise high-risk group determination even with the expectation of higher false positivity.