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. 2019 Apr 12;6:48. doi: 10.3389/fcvm.2019.00048

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Copyright © 2019 Maisch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Epidemiological shift in the Myocarditis Registry from entero-(green line) and adenoviruses (brown line) to Parvovirus B 19 (dark blue line) in the late 1980-ties. The number of patients with nonviral myocarditis (light blue line) varied from 50 to 80% in the same time span. (B) PCR-based etiology of viral and autoreactive myocarditis and dilated cardiomyopathy without inflammation (4th column) [modified from Pankuweit et al. (60)]. PCR-Based etiology of myocarditis and dilated cardiomyopathy. Investigation of endomyocardial biopsies from 3345 patients (1997–2003).