Table 2.
Risk of recurrent stroke, all-cause mortality, and poor functional outcome stratified by platelet count levels at 1-year follow-up.
| Outcomes | Quintile of platelet count, × 109/L | Events n (%) | Model 1a | P-value | Model 2b | P-value | Model 3c | P-value |
|---|---|---|---|---|---|---|---|---|
| Adjusted HRd/ORe (95% CI) | Adjusted HRd/ORe (95% CI) | Adjusted HRd/ORe (95% CI) | ||||||
| Recurrent stroke | Q1, 100–155 | 255 (7.7) | 1.13 (0.94–1.35) | 0.199 | 1.10 (0.92–1.32) | 0.306 | 1.14 (0.95–1.37) | 0.164 |
| Q2, 156–185 | 239 (7.0) | 1.06 (0.88–1.28) | 0.522 | 1.04 (0.87–1.26) | 0.646 | 1.05 (0.87–1.26) | 0.621 | |
| Q3, 186–212 | 212 (6.3) | 1 | 1 | 1 | ||||
| Q4, 213–248 | 249 (7.3) | 1.18 (0.98–1.42) | 0.076 | 1.18 (0.98–1.42) | 0.074 | 1.11 (0.93–1.34) | 0.254 | |
| Q5, 249–450 | 286 (8.5) | 1.39 (1.17–1.67) | <0.001 | 1.40 (1.17–1.67) | <0.001 | 1.28 (1.06–1.54) | 0.001 | |
| All-cause mortality | Q1, 100–155 | 316 (9.6) | 1.18 (0.99–1.40) | 0.065 | 1.14 (0.96–1.35) | 0.145 | 1.16 (0.95–1.43) | 0.159 |
| Q2, 156–185 | 285 (8.4) | 1.13 (0.95–1.35) | 0.171 | 1.10 (0.92–1.32) | 0.279 | 1.14 (0.94–1.37) | 0.191 | |
| Q3, 186–212 | 217 (6.5) | 1 | 1 | 1 | ||||
| Q4, 213–248 | 237 (7.0) | 1.12 (0.93–1.35) | 0.227 | 1.13 (0.94–1.36) | 0.189 | 1.07 (0.88–1.31) | 0.486 | |
| Q5, 249–450 | 322 (9.5) | 1.62 (1.36–1.93) | <0.001 | 1.66 (1.39–1.97) | <0.001 | 1.43 (1.19–1.73) | <0.001 | |
| Poor functional outcome | Q1, 100–155 | 780 (23.7) | 1.19 (1.05–1.35) | 0.007 | 1.17 (1.03–1.33) | 0.017 | 1.19 (1.02–1.38) | 0.025 |
| Q2, 156–185 | 718 (21.1) | 1.14 (1.01–1.30) | 0.040 | 1.12 (0.99–1.28) | 0.073 | 1.16 (0.99–1.35) | 0.052 | |
| Q3, 186–212 | 585 (17.5) | 1 | 1 | 1 | ||||
| Q4, 213–248 | 685 (20.1) | 1.27 (1.12–1.44) | <0.001 | 1.27 (1.12–1.45) | <0.001 | 1.28 (1.10–1.49) | 0.002 | |
| Q5, 249–450 | 789 (23.4) | 1.61 (1.42–1.83) | <0.001 | 1.63 (1.44–1.85) | <0.001 | 1.49 (1.28–1.74) | <0.001 |
OR, odds ratio; HR, hazard ratio; CI, confidence interval; Q, quintile.
Model 1: adjusted for age, gender and BMI.
Model 2: adjusted for age, gender, BMI, myocardial infarction, atrial fibrillation or flutter, drinking, smoking, hypertension, medication history of antihypertensive drugs.
Model 3: adjusted for age, gender, BMI, myocardial infarction, atrial fibrillation or flutter, drinking, smoking, hypertension, medication history of antihypertensive drugs, NIHSS score on admission, white blood cell, and mRS score at discharge.
Adjusted HR for recurrent stroke and all-cause mortality.
Adjusted OR for poor functional outcome.