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. 2019 Mar 18;6(1):41. doi: 10.3390/medicines6010041

Table 7.

Imaging modalities for the diagnosis of NAFLD.

Imaging Modality Clinical Utility Limitations
Ultrasound Abdomen [98] Widely available and convenient
Sensitivity and specificity for diagnosing fatty liver disease is 85% and 94% respectively
Operator dependent
Lacks sensitivity in NAFLD patients with less than 30% steatosis on liver biopsy
CT abdomen [99] Limited clinical utility in diagnosing NAFLD Radiation hazard, introduces contrast-related risks, has low sensitivity for hepatic fat mapping
Magnetic resonance spectroscopy [99,100,101] Allows for quantification of hepatic fat Not available on all scanner
Transient Elastography (Fibroscan) [102,103] Sensitivity of 88% with a negative predictive value of 90% in detecting advanced fibrosis Presence of ascites, obese patients or presence of acute inflammation
Magnetic Resonance elastography [104,105] Sensitivity of 86% and specificity of 91% for diagnosing advanced fibrosis Limited availability, expertise to interpret the results, cost of the procedure, presence of metal implants, patient’s size and claustrophobia
Shear wave elastography (SWE) [106] Sensitivity of 90% and the specificity of 88% in detecting advanced fibrosis Limited evidence available current and needs further research on its clinical utility