Table 7.
Imaging Modality | Clinical Utility | Limitations |
---|---|---|
Ultrasound Abdomen [98] | Widely available and convenient Sensitivity and specificity for diagnosing fatty liver disease is 85% and 94% respectively |
Operator dependent Lacks sensitivity in NAFLD patients with less than 30% steatosis on liver biopsy |
CT abdomen [99] | Limited clinical utility in diagnosing NAFLD | Radiation hazard, introduces contrast-related risks, has low sensitivity for hepatic fat mapping |
Magnetic resonance spectroscopy [99,100,101] | Allows for quantification of hepatic fat | Not available on all scanner |
Transient Elastography (Fibroscan) [102,103] | Sensitivity of 88% with a negative predictive value of 90% in detecting advanced fibrosis | Presence of ascites, obese patients or presence of acute inflammation |
Magnetic Resonance elastography [104,105] | Sensitivity of 86% and specificity of 91% for diagnosing advanced fibrosis | Limited availability, expertise to interpret the results, cost of the procedure, presence of metal implants, patient’s size and claustrophobia |
Shear wave elastography (SWE) [106] | Sensitivity of 90% and the specificity of 88% in detecting advanced fibrosis | Limited evidence available current and needs further research on its clinical utility |