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. 2019 Jan 23;7(1):5. doi: 10.3390/proteomes7010005

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Volcano plot of mass spectrometry results. Proteins that are significantly upregulated in sex by genotype conditions: (a) shows the proteins significantly upregulated in female Fgf14^−/− compared to Fgf14^+/+ mice; and (b) shows the proteins significantly upregulated in male Fgf14^−/− compared to Fgf14^+/+ mice. The Y-axis represents negative log10 (p-value) based on the test statistic, and the X-axis shows proteins with a positive log₂ fold change (FC) as upregulated (red), and negative values as downregulated (green) proteins in the Fgf14^−/− mice, respectively.