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Structure characterization of PLGA 75:25 microspheres obtained with increased polymer concentration, p < 0.05. The average diameters and porosity (%) were calculated based on SEM images with image analysis software ImageJ and weight ratios as depicted in Section 2.6.
| Factor | PLGA 75.25 Concentration (% w/v) | ||
|---|---|---|---|
| 1% | 3% | 5% | |
| Average diameter (μm) | 91 ± 1 | 86 ± 2 | 87 ± 3 |
| Average surface pore diameter (μm) | 11 ± 3 | 10 ± 4 | 8 ± 3 |
| Porosity (%) | 83.7 | 71.3 | 68.4 |
