Table 1.

Recommendations for clinical practice (using the GRADE system) for different neurorehabilitation approaches in TBI. TBI—traumatic brain injury; GRADE—Grading of Recommendations Assessment, Development, and Evaluation.

Quality of Evidence	Rehabilitation	Patient Category	Outcome	Potential of Cost Savings	Recommendation (GRADE System)
High	Intensive	Severe TBI	Earlier gain in independence Reduced length of stay (LOS) in hospital	+	Strongly recommended
Moderate/high	Specialist	Very severe/severe TBI	Improved independence Reduced ongoing care	++	Recommended
	Specialist vocational programmes	Moderate/severe TBI	Gain in productivity	++	Strongly recommended
Moderate	Early	Severe TBI	Earlier gain in independence Reduced LOS in hospital	+	Recommended
	Community based	Moderate/severe TBI	Improved productivity	++	Recommended
Low/moderate	Behavioural management programmes	TBI with severe behavioural problems	Improved social behaviour reduced ongoing care support	+	Recommended
	Late and ongoing rehabilitation	Moderate/severe TBI with enduring disability	Maintenance of independence/productivity	+/−	Conditionally recommended