3.13. Analysis.
Comparison 3 COMPARISON 3. ARIPIPRAZOLE versus RISPERIDONE, Outcome 13 Mental state: 9. average scores of various scale (high=poor, skewed data).
| Mental state: 9. average scores of various scale (high=poor, skewed data) | |||||
|---|---|---|---|---|---|
| Study | Intervention | Mean | SD | N | Note |
| SANS endpoint scale score | |||||
| Tong 2007 | Aripiprazole | 10. 6 | 14. 4 | 36 | |
| Tong 2007 | Risperidone | 14. 2 | 20. 3 | 32 | |
| PANSS general pathology subscale score | |||||
| Chang 2007 | Aripiprazole | 18.65 | 11.64 | 50 | |
| Chang 2007 | Risperidone | 19.15 | 10.95 | 50 | |
| Xie 2008 | Aripiprazole | 19. 24 | 12. 18 | 42 | |
| Xie 2008 | Risperidone | 19. 36 | 10. 71 | 42 | |
| PANSS negative symptom subscale score | |||||
| Chang 2007 | Aripiprazole | 12.04 | 6.46 | 50 | |
| Chang 2007 | Risperidone | 12.08 | 6.56 | 50 | |
| CuiMeng 2008 | Aripiprazole | 9. 2 | 8. 7 | 60 | |
| CuiMeng 2008 | Ziprasidone | 12. 3 | 8. 2 | 60 | |
| Deng 2008 | Aripiprazole | 14.89 | 3.89 | 25 | |
| Deng 2008 | Risperidone | 13.01 | 7.362 | 25 | |
| Guo 2006 | Aripiprazole | 12.4 | 3.9 | 18 | |
| Guo 2006 | Risperidone | 15.8 | 9.2 | 20 | |
| Ji 2007 | Aripiprazole | 12.71 | 4.58 | 32 | |
| Ji 2007 | Risperidone | 15.19 | 9.57 | 32 | |
| Li 2007d | Aripiprazole | 15.9 | 5.8 | 60 | |
| Li 2007d | Risperidone | 12.3 | 6.6 | 60 | |
| Li 2009b | Aripiprazole | 11.1 | 6.2 | 30 | |
| Li 2009b | Risperidone | 11.1 | 6.1 | 30 | |
| Li X 2007 | Aripiprazole | 12.2 | 7.2 | 36 | |
| Li X 2007 | Risperidone | 12.5 | 8.4 | 35 | |
| Liu 2006a | Aripiprazole | 11.3 | 7.4 | 45 | |
| Liu 2006a | Risperidone | 10.8 | 7.7 | 45 | |
| Lv 2007 | Aripiprazole | 11. 5 | 3. 8 | 40 | |
| Lv 2007 | Risperidone | 12. 5 | 6. 8 | 40 | |
| Mai 2005 | Aripiprazole | 12. 9 | 7. 1 | 36 | |
| Mai 2005 | Risperidone | 13. 9 | 6. 1 | 36 | |
| Pan 2007 | Aripiprazole | 11.9 | 7.2 | 30 | |
| Pan 2007 | Risperidone | 13.9 | 6.1 | 30 | |
| Shan 2008 | Aripiprazole | 11.2 | 5.8 | 30 | |
| Shan 2008 | Risperidone | 11.4 | 5.4 | 30 | |
| Song 2009 | Aripiprazole | 11.7 | 6.5 | 30 | |
| Song 2009 | Risperidone | 12.8 | 5.9 | 30 | |
| Su 2007 | Aripiprazole | 11. 4 | 7. 6 | 39 | |
| Su 2007 | Risperidone | 12. 6 | 6. 7 | 39 | |
| Tang 2006 | Aripiprazole | 10.9 | 5.3 | 37 | |
| Tang 2006 | Risperidone | 11.1 | 5.8 | 35 | |
| Tang 2007 | Aripiprazole | 11.9 | 5.7 | 30 | |
| Tang 2007 | Risperidone | 11.2 | 5.8 | 30 | |
| Tu 2009 | Aripiprazole | 11.3 | 6.5 | 35 | |
| Tu 2009 | Risperidone | 13.8 | 6.7 | 33 | |
| Wen 2009a | Aripiprazole | 14.89 | 3.88 | 40 | |
| Wen 2009a | Risperidone | 13.02 | 7.34 | 40 | |
| Xie 2008 | Aripiprazole | 11. 95 | 5. 69 | 42 | |
| Xie 2008 | Risperidone | 12. 32 | 6. 17 | 42 | |
| Xie 2010 | Aripiprazole | 10.76 | 4.53 | 40 | |
| Xie 2010 | Risperidone | 10.78 | 6.11 | 40 | |
| Yang 2008b | Aripiprazole | 12.1 | 6.9 | 45 | |
| Yang 2008b | Risperidone | 11.9 | 7.1 | 45 | |
| Ye 2005a | Aripiprazole | 11. 8 | 4. 3 | 29 | |
| Ye 2005a | Risperidone | 12. 3 | 8. 2 | 29 | |
| Zhang 2008b | Aripiprazole | 9.2 | 8.7 | 20 | |
| Zhang 2008b | Risperidone | 13.5 | 6.9 | 20 | |
| Zhi 2005 | Aripiprazole | 10.7 | 6.5 | 40 | |
| Zhi 2005 | Risperidone | 12.8 | 5.9 | 40 | |
| Zhou 2008 | Aripiprazole | 10. 8 | 5. 5 | 70 | |
| Zhou 2008 | Risperidone | 11. 2 | 5. 7 | 70 | |
| Zhu 2010 | Aripiprazole | 10.40 | 6.57 | 22 | |
| Zhu 2010 | Risperidone | 11.67 | 4.31 | 28 | |
| PANSS positive symptom subscale score | |||||
| Chang 2007 | Aripiprazole | 16.82 | 11.66 | 50 | |
| Chang 2007 | Risperidone | 17.64 | 11.76 | 50 | |
| Chen 2010 | Aripiprazole | 10.58 | 5.33 | 32 | |
| Chen 2010 | Risperidone | 11.31 | 5.33 | 32 | |
| Fan 2010 | Aripiprazole | 10.66 | 4.71 | 30 | |
| Fan 2010 | Risperidone | 8.96 | 4.93 | 30 | |
| Feng 2006 | Aripiprazole | 5.18 | 2.04 | 30 | |
| Feng 2006 | Risperidone | 4.91 | 3.14 | 30 | |
| Hu 2010 | Aripiprazole | 10.56 | 4.52 | 25 | |
| Hu 2010 | Risperidone | 11.16 | 6.21 | 25 | |
| Li 2007a | Aripiprazole | 10.39 | 6.02 | 30 | |
| Li 2007a | Risperidone | 10.31 | 5.11 | 30 | |
| Li 2007d | Aripiprazole | 17.2 | 9.3 | 60 | |
| Li 2007d | Risperidone | 12.1 | 3.4 | 60 | |
| Li X 2007 | Aripiprazole | 12 | 8 | 36 | |
| Li X 2007 | Risperidone | 13.2 | 7.3 | 35 | |
| Lian 2008 | Aripiprazole | 8.9 | 4.1 | 43 | |
| Lian 2008 | Risperidone | 11.5 | 5.9 | 43 | |
| Liu 2006a | Aripiprazole | 12.4 | 7.2 | 45 | |
| Liu 2006a | Risperidone | 12.1 | 7.5 | 45 | |
| Liu 2008c | Aripiprazole | 9. 59 | 3. 17 | 37 | |
| Liu 2008c | Risperidone | 10. 29 | 5. 47 | 35 | |
| Mu 2008 | Aripiprazole | 10. 95 | 5. 07 | 50 | |
| Mu 2008 | Risperidone | 11. 50 | 6. 02 | 50 | |
| Song 2009 | Aripiprazole | 10.7 | 5.3 | 30 | |
| Song 2009 | Risperidone | 11.3 | 5.9 | 30 | |
| Su 2007 | Aripiprazole | 10. 8 | 7. 5 | 39 | |
| Su 2007 | Risperidone | 12. 2 | 6. 8 | 39 | |
| Tang 2006 | Aripiprazole | 10.6 | 5.1 | 37 | |
| Tang 2006 | Risperidone | 11.2 | 6.0 | 35 | |
| Tang 2007 | Aripiprazole | 10.1 | 5.3 | 30 | |
| Tang 2007 | Risperidone | 8.6 | 6.5 | 30 | |
| Tang 2010 | Aripiprazole | 10.2 | 4.1 | 38 | |
| Tang 2010 | Risperidone | 10.6 | 5.8 | 40 | |
| Wang 2007e | Aripiprazole | 9.7 | 5.8 | 30 | |
| Wang 2007e | Risperidone | 10.1 | 5.6 | 30 | |
| Xie 2008 | Aripiprazole | 17. 21 | 10. 97 | 42 | |
| Xie 2008 | Risperidone | 17. 33 | 11. 82 | 42 | |
| Xie 2010 | Aripiprazole | 8.94 | 2.13 | 40 | |
| Xie 2010 | Risperidone | 9.41 | 4.78 | 40 | |
| Yang 2008b | Aripiprazole | 12.2 | 6.8 | 45 | |
| Yang 2008b | Risperidone | 12.3 | 7.1 | 45 | |
| Yu 2008 | Aripiprazole | 9.7 | 5.53 | 50 | |
| Yu 2008 | Risperidone | 10.1 | 5.8 | 50 | |
| Zhang 2007a | Aripiprazole | 8.0 | 2.4 | 25 | |
| Zhang 2007a | Risperidone | 9.31 | 5.12 | 25 | |
| Zhang 2008 | Aripiprazole | 9.77 | 6.78 | 30 | |
| Zhang 2008 | Risperidone | 11.17 | 5.75 | 30 | |
| Zhang 2008b | Aripiprazole | 13.1 | 8.6 | 20 | |
| Zhang 2008b | Risperidone | 9.1 | 7.6 | 20 | |
| Zhi 2005 | Aripiprazole | 10.7 | 5.3 | 40 | |
| Zhi 2005 | Risperidone | 11.3 | 5.9 | 40 | |