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. 2014 Jan 2;2014(1):CD006569. doi: 10.1002/14651858.CD006569.pub5

Cheng 2009.

Methods Allocation: randomised, no further details.
Blindness: unclear.
 Duration: eight weeks.
 Design: parallel.
 Setting: inpatient, China.
Participants Diagnosis: schizophrenia (CCMD‐3). PANSS of 60 or more, SANS of 60 or more.
 N = 86.
 Age: aripiprazole group: mean = (29.35 ± 7.6) years; ziprasidone group: mean= (30.28 ± 8.1) years.
Gender: aripiprazole group: 25 male, 18 female; ziprasidone group: 26 male, 17 female.
 History: aripiprazole group: mean = (5.23 ± 2.81) years; ziprasidone group: mean = (5.16 ± 2.6) years. Age at onset not reported.
Interventions 1. Aripiprazole: Dose range: 5‐20 mg/day. Mean = (11.7 ± 1.2) mg/day. N = 43.
 2. Ziprasidone: Dose range: 20‐120 mg/day. Mean = (86.26 ± 10.2) mg/day. N = 43.
Outcomes Global state: PANSS score decreased rate (recovery: ≥ 75%, markedly improved: 50%‐75%, improved: 25%‐50%, no effect: < 25%).
Mental state: PANSS total score, PANSS positive subscale score, PANSS negative subscale score, PANSS general pathological subscale score. SANS total score score.
Adverse effects.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomised, no further details.
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not reported.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Unclear if outcome was assessed blindly.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No incomplete data.
Selective reporting (reporting bias) High risk Data on CGI‐GI score, TESS score, blood routine, urine routine, use of benzodiazepines and anticholinergic medication were missing.
Other bias Low risk None obvious.