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. 2014 Jan 2;2014(1):CD006569. doi: 10.1002/14651858.CD006569.pub5

Liu 2009.

Methods Allocation: randomised, no further details.
Blindness: unclear.
 Duration: eight weeks.
 Design: parallel.
 Setting: inpatient and outpatient, China.
Participants Diagnosis: schizophrenia (CCMD‐3). PANSS of 60 or more.
 N = 68.
 Age: aripiprazole group: mean = (26.1 ± 7.5) years; olanzapine group: mean = (27.4 ± 8.4) years.
Gender: aripiprazole group: 18 male, 16 female; olanzapine group: 17 male, 17 female.
 History: aripiprazole group: mean = (6.9 ± 3.4) years; olanzapine group: mean = (6.5 ± 3.6) years. Age at onset not reported.
Interventions 1. Aripiprazole: Dose range: 10‐30 mg/day. Mean = (19.7 ± 5.3) mg/day. N = 34.
 2. Olanzapine: Dose range: 10‐20 mg/day. Mean = (15.4 ± 4.5) mg/day. N = 34.
Outcomes Mental state: PANSS total score, PANSS positive subscale score, PANSS negative subscale score, PANSS psychopathological subscale score.
Quality of life: GQOLI‐ 74 total score, GQOLI‐ 74 material life score, GQOLI‐ 74 physical health score, GQOLI‐ 74 mental health score, GQOLI‐ 74 social function score.
Adverse effects.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomised, no further details.
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not reported.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Unclear if outcome was assessed blindly.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Unclear if there were incomplete data.
Selective reporting (reporting bias) High risk Data on TESS total score, use of benzodiazepines and benzhexol were missing.
Other bias Low risk None obvious.