Tang 2006.

Methods	Allocation: simple randomisation. Blindness: unclear. Duration: eight weeks. Design: parallel. Setting: inpatient, China.
Participants	Diagnosis: schizophrenia (CCMD‐3). PANSS of 60 or more. N = 72. Age: aripiprazole group: 18～61 years, mean = (31.3 ± 6.2) years; risperidone group: 16～60 years, mean = (30.8 ± 6.1) years. Gender: aripiprazole group: 37 female; risperidone group: 35 female. History: aripiprazole group: 1 month～4.5 years; risperidone group: 1 month～4.6 years. Age at onset not reported.
Interventions	1. Aripiprazole: Dose range: 5‐30 mg/day. Mean = (10 ± 5.22) mg/day. N = 37. 2. Risperidone: Dose range: 1‐6 mg/day. Mean = (3.5 ± 0.81) mg/day. N = 35.
Outcomes	Global state: PANSS score decreased rate (recovery: ≥ 75%, markedly improved: 50%‐74%, improved: 25%‐49%, no effect: < 25%). Mental state: PANSS total score, PANSS positive subscale score, PANSS negative subscale score, PANSS psychopathological subscale score. Adverse effects. Unable to use ‐ Adverse effects: TESS total score, use of benzodiazepines, propranolol and benzhexol (no data).
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Simple randomisation.
Allocation concealment (selection bias)	Unclear risk	Not reported.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not reported.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Unclear if outcome was assessed blindly.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No incomplete data.
Selective reporting (reporting bias)	High risk	Data on TESS score, use of benzodiazepines, propranolol and benzhexol were missing.
Other bias	Low risk	None obvious.