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. 2014 Jan 2;2014(1):CD006569. doi: 10.1002/14651858.CD006569.pub5

Wang 2007.

Methods Allocation: randomised, no further details.
Blindness: unclear.
 Duration: eight weeks.
 Design: parallel.
 Setting: outpatient, China.
Participants Diagnosis: schizophrenia (CCMD‐3). BPRS of 35 or more.
 N = 95.
 Age: aripiprazole group: 16~54 years. mean = (24.4 ± 13.2) years; risperidone group: 13~67 years, mean = (25. 4 ± 14. 6) years.
Gender: aripiprazole group: 22 male, 24 female; risperidone group: 23 male, 26 female.
 History: not reported. Age at onset not reported.
Interventions 1. Aripiprazole: Dose range: 5‐30 mg/day. Mean dose: not reported. N = 46.
 2. Risperidone: Dose range: 1‐6 mg/day. Mean dose: not reported. N = 49.
Outcomes Global state: PANSS score decreased rate (recovery: ≥ 75%, markedly improved: 50%‐75%, improved: 25%‐50%, no effect: < 25%).
Mental state: PANSS total score.
Leaving the study early.
Adverse effects.
Unable to use ‐
 Adverse effects: TESS total score, blood routine, use of benzodiazepines and anticholinergic medication (no data).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomised, no further details.
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not reported.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Unclear if outcome was assessed blindly.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Total proportion of drop‐out was 3.15% and the data of the two groups were balanced (2/46: 1/49). Two because of adverse effect, one due to economic issue.
Selective reporting (reporting bias) High risk Data on TESS total score, blood routine, use of benzodiazepines and anticholinergic medication were missing.
Other bias Low risk None obvious.