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. 2014 Jan 2;2014(1):CD006569. doi: 10.1002/14651858.CD006569.pub5

Zhao 2006.

Methods Allocation: randomised, no further details.
Blindness: unclear.
 Duration: eight weeks.
 Design: parallel.
 Setting: inpatient, China.
Participants Diagnosis: schizophrenia (CCMD‐3). PANSS of 60 or more.
 N = 68.
Age: aripiprazole group: mean = (24.3 士 9.4) years; quetiapine group: 18‐51 years, mean = (26.7 ± 8.4) years.
Gender: male and female
 History: aripiprazole group: mean = (23 土 13) months; quetiapine group: mean =(4. 5 ± 2.9) years. Age at onset not reported.
Interventions 1. Aripiprazole: Dose range: 10‐30 mg/day. Mean dose = not reported. N = 34.
 2. Quetiapine: Dose range: 100‐750 mg/day. Mean dose = (465 ± 132) mg/day. N = 34.
Outcomes Global state: PANSS score decreased rate (recovery: ≥ 75%, markedly improved: 50%‐75%, improved: 30%‐50%, no effect: < 30%).
Mental state: PANSS total score.
Unable to use ‐
 Mental state: PANSS positive subscale score, PANSS negative subscale score, PANSS general psychogenic pathological subscale score.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomised, no further details.
Allocation concealment (selection bias) Unclear risk Not described.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No incomplete outcome data.
Selective reporting (reporting bias) High risk TESS score was measured, but not reported.
Other bias Low risk None obvious.