Zhao 2006.
Methods | Allocation: randomised, no further details. Blindness: unclear. Duration: eight weeks. Design: parallel. Setting: inpatient, China. |
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Participants | Diagnosis: schizophrenia (CCMD‐3). PANSS of 60 or more.
N = 68. Age: aripiprazole group: mean = (24.3 士 9.4) years; quetiapine group: 18‐51 years, mean = (26.7 ± 8.4) years. Gender: male and female History: aripiprazole group: mean = (23 土 13) months; quetiapine group: mean =(4. 5 ± 2.9) years. Age at onset not reported. |
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Interventions | 1. Aripiprazole: Dose range: 10‐30 mg/day. Mean dose = not reported. N = 34. 2. Quetiapine: Dose range: 100‐750 mg/day. Mean dose = (465 ± 132) mg/day. N = 34. | |
Outcomes | Global state: PANSS score decreased rate (recovery: ≥ 75%, markedly improved: 50%‐75%, improved: 30%‐50%, no effect: < 30%). Mental state: PANSS total score. Unable to use ‐ Mental state: PANSS positive subscale score, PANSS negative subscale score, PANSS general psychogenic pathological subscale score. |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomised, no further details. |
Allocation concealment (selection bias) | Unclear risk | Not described. |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No incomplete outcome data. |
Selective reporting (reporting bias) | High risk | TESS score was measured, but not reported. |
Other bias | Low risk | None obvious. |