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. 2019 Apr 12;10:155. doi: 10.3389/fendo.2019.00155

Figure 6.

Figure 6

GLP-1 receptor immunoreactivity in non-human primate smooth muscle cells. (A) GLP-1R immunoreactivity in non-human primate smooth muscle cells of a vas afferens (va) arteriole at the vascular pole. Note the absence of signal in the macula densa (md), tubuli (t), glomerulus (*), and endothelial cells within an arteriole (arrow). (B,C) Near-adjacent sections showing double labeling for GLP-1R (green)/renin (red) and GLP-1R (green)/SMA (red), respectively. (B′,C′) Same as (B,C), respectively, with red fluorescence digitally removed to highlight GLP-1R immunoreactivity. (B″,C″) Same as (B,C), respectively, with green fluorescence digitally removed to highlight renin and SMA immunoreactivity, respectively. Scale bars correspond to 50 μm.GLP-1R, glucagon-like peptide 1 receptor; SMA, smooth muscle actin. Reproduced with permission from Pyke et al. (73). By permission of Oxford University Press on behalf of the Endocrine Society, available at: https://academic.oup.com/endo/article/155/4/1280/2423090?searchresult=1. This figure is not included under the CC-BY license of this publication. For permissions, please contact journals.permissions@oup.com.