Table 2.

Summary of GLP-1 receptor location in the mouse brain and comparison with external references.

Structure		Area	Protein	mRNA	Cork et al. (114) (Protein)	AIBS mRNA
Telencephalon	ACB	Nucleus accumbens	+	+	+	+
	AOB	Accessory olfactory bulb	+	+	+	+
	BMA	Basomedial amygdalar nucleus	+	–	+	+
	BST	Bed nucleus of stria terminalis	+	+	+	+
	CeA	Central amygdala	+	+	+	+
	CeA/AAA	Central amygdala/anterior amygdalar area	+	+	+	+
	COA	Cortical amygdalar area	+	–	+	+
	DG	Dentate gyrus	+	+	+	+
	LPO	Lateral preoptic area	+	+	+	+
	LS	Lateral septal nucleus	+	+	+	+
	NLOT/COA	Nucleus of the lateral olfactory tract/cortical amygdalar area	+	–	+	+
	OV	Vascular organ of the laminae terminalis	+	NA	+	NA
	PA	Posterior amygdalar nucleus	+	–	+	+
	SF	Septofimbrial nucleus	+	+	NA	+
	SFO	Subfornical organ	+	+	+	+
	TRS	Triangular nucleus of septum	–	+	NA	+
	TT	Tenia tecta	+	+	+	+
Diencephalon	ARH	Arcuate hypothalamic nucleus	+	+	+	+
	DMH	Dorsomedial hypothalamic nucleus	+	+	+	+
	GENd	Geniculate group, dorsal thalamus	+	–	+	+
	Hb	Habenula	+	–	+	+
	LHA	Lateral hypothalamic nucleus	+	+	+	+
	ME	Median eminence	+	–	NA	+
	PH	Posterior hypothalamic nucleus	+	–	+	+
	PP	Peripeduncular nucleus	+	+	NA	+
	PVH	Paraventricular hypothalamic nucleus	+	+	+	+
	RCH	Retrochiasmatic area	+	–	+	+
	SO	Supraoptic nucleus	+	+	NA	+
	TU	Tuberal nucleus	+	+	NA	+
	ZI	Zona incerta	+	+	+	+
Mesencephalon	APN	Anterior pretectal nucleus	+	+	+	+
	DR	Dorsal raphe	+	–	NA	+
	MM	Medial mammillary nucleus	+	–	+	+
	MPT	Medial pretectal area	+	+	+	+
	MRN	Midbrain reticular nucleus	+	–	NA	+
	PAG	Periaqueductal gray	+	+	+	+
	PPT	Posterior pretectal area	+	+	+	+
	SCs	Superior colliculus, sensory related	–	+	NA	+
	SCm	Superior colliculus, motor related	+	+	NA	+
	SCTV	ventral spinocerebellar tract	+	–	NA	+
	SNr	Substantia nigra, reticular part	+	+	NA	+
	SNc	Substantia nigra, compact part	+	+	NA	+
Pons	NI	Nucleus incertus	+	–	NA	+
	NLL	Nucleus of the lateral lemniscus	+	–	NA	+
	PB	Parabrachial nucleus	+	+	NA	+
	PCG	Pontine central gray	+	–	NA	+
	PG	Pontine gray	+	+	NA	+
	PRNc	Pontine reticular nucleus, caudal part	–	+	NA	+
	PRNr	Pontine reticular nucleus	–	+	NA	+
	PSV	Principal sensory nucleus of the trigeminal	+	+	NA	+
	SOC	Superior olivary complex	+	–	NA	+
Medulla	AMB	Nucleus ambiguus	–	+	NA	+
	AP	Area postrema	+	+	+	+
	CU	Cuneate nucleus	+	+	NA	+
	DMX	Dorsal motor nucleus of the vagus nerve	+	–	NA	+
	ECU	External cuneate nucleus	+	+	NA	+
	FL	Flocculus (cerebellum)	+	–	NA	+
	IO	Inferior olivary complex	+	+	+	+
	LRNm	Lateral reticular nucleus, magnocellular part	+	+	NA	+
	MARN	Magnocellular reticular nucleus	–	+	NA	+
	MDRN	Medullary reticular nucleus	–	+	NA	+
	MV	Medial vestibular nucleus	+	+	NA	+
	NTS	Nucleus tractus solitarus	+	+	+	+
	PARN	Parvocellular reticular nucleus	–	+	NA	+
	SPVC	Spinal nucleus of the trigeminal, caudal part	+	+	NA	+

Presence (+) or absence (–) of GLP-1R protein and mRNA in mouse brain. The two right-hand columns indicate whether GLP-1R was observed as a protein or mRNA (AIBS). AIBS, Allen Brain Atlas; GLP-1R, glucagon-like peptide 1 receptor; NA, not assessed/reported. Source: Jensen et al. (115).