Table 2.
Classification of the upregulated and downregulated genes involved in the significant bioprocesses of the XYS group compared with the model group.
| Term | Genes | P-value | |
|---|---|---|---|
| Upregulated genes in XYS group | Developmental process | WNT5A, TACR3, EVX2, GRB2, C5, STRN, HEMGN, APOA5, ERAF, SOX18, GPNMB, PCDHA13, FRS2, FIGF, FANCA, RUNX3, ANAPC2, LYN, ARHGEF7, SMAD6, MYO1E, CDK6, MALT1, DBH, PRPH2, IRS1, GNAT2, ATP7A, ALOX15, UCP3, HDAC1, SPATA18, NAB1, USH1C, TGFB1I1, COL1A1, PRM2, TCF12 | 2.18E-04 |
| Multicellular organismal process | TACR3, EVX2, STRN, HEMGN, OLR1392, APOA5, ERAF, SOX18, FRS2, FANCA, ANAPC2, OLR790, LYN, ARHGEF7, LOC367539, CDK6, IRS1, SAG, MMP11, ALOX15, OLR450, SPATA18, NAB1, USH1C, OLR194, COL1A1, TGFB1I1, WNT5A, OLR1073, GRB2, C5, RPL10L, IL23A, GPNMB, PCDHA13, OLR112, FIGF, RUNX3, OLR1609, OLR220, MYO1E, SMAD6, MALT1, DBH, PRPH2, GNAT2, ATP7A, OLR1384, HDAC1, OLR1726, PRM2, TCF12 | 1.03E-03 | |
| Immune system process | LYN, MYO1E, SMAD6, RT1-M1-2, C5, CXCL9, MALT1, CDK6, CXCL11, DBH, ATP7A, IL23A, ERAF | 1.33E-02 | |
| Response to stimulus | WNT5A, TACR3, OLR1073, PANX1, GRB2, C5, RT1-M1-2, CXCL9, STRN, CXCL11, IL23A, OLR1392, SLC2A1, APOA5, OLR112, OLR1609, OLR790, LYN, OLR220, SMAD6, NEIL1, TRIM25, MALT1, DBH, PRPH2, IRS1, SAG, CYP4B1, GNAT2, PCK1, ATP7A, OLR1384, HAO1, CRHR2, UCP3, HDAC1, OLR450, OLR1726, OLR194, TGFB1I1, COL1A1 | 4.47E-02 | |
| Down regulated genes in XYS group | Multicellular organismal process | IBSP, PCDHA6, OLR851, ERBB4, EFNA1, EFNA2, MUTED, PGAM2, DNASE1L2, EPHB3, CDH22, GPX2, OLR488, SOSTDC1, NOS3, COL8A1, TWIST1, OTOP1, FANCC, NES, PTGER3, ESRRB, SMAD5, ACACA, DLL3, ANG1, OLR247, DPYSL3, VAX1, SLCO1A5, TNNI2, MSX1, F5, ARRB2, KCNJ8, CLDN1, OLR1288, FABP1, SEMA4D, OLR855, CTNS | 3.22E-03 |
| Developmental process | IBSP, PCDHA6, ERBB4, EFNA1, EFNA2, MUTED, DNASE1L2, EPHB3, CDH22, SOSTDC1, NOS3, COL8A1, TWIST1, OTOP1, FANCC, NES, ESRRB, SMAD5, DLL3, ANG1, DPYSL3, VAX1, SLCO1A5, MSX1, KCNJ8, CLDN1, SEMA4D, CTNS | 4.58E-03 | |
| Biological adhesion | CDH22, PCDHA6, IBSP, WISP2, F5, PCDHB3, CLDN1, LOC498972 | 2.8E-02 |
P < 0.05 was considered to be statistically significant, and arranged in the order of the significant difference. Genes: The differential genes which were screened in the bioprocess in this experiment.