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. Author manuscript; available in PMC: 2019 Apr 19.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2018 May;11(5):e006119. doi: 10.1161/CIRCEP.117.006119

Table 1.

Selected Studies for the Systematic Review: Baseline Information

Year Author Publication
Type
Study Type Search Database Study
Size, n
Type of
Ablation
Type of Driver
Mapping
Follow-
Up, mo
Persistent
AF
Redo
Ablation
Age, y Male
Sex
LA Size,
mm
Ejection
Fraction, %
2012 Narayan et al7* Manuscript Multicenter, controlled PubMED 107 Driver+PVI FIRM 9.1 0.85 0.42 63±9 0.94 48.0±7 53±1 5
2014 Haissaguerre et al8 Manuscript Single center, case series PubMED 193 Driver+PVI ECVUE 12.0 1.00 0.20 59±11 0.77 48.0±7 52±13
2014 Atienza et al9 Manuscript Multicenter, randomized Cochrane 232 Driver+PVI Dominant
frequency
12.0 1.00 0 55±9 0.81 45.0±7 60
2015 Sommer et al13 Manuscript Single center, case series PubMED 1820 Driver+PVI FIRM 0.90 0.50 61 ±8 0.70 45.9±5 55±8
2015 Tomassoni et al14 Manuscript Single center, case series Review of References 80 Driver+PVI FIRM 16.0 0.76 0.46 62±9 0.75 55.0±7 52 ±8
2015 Rashid et al15 Manuscript Single center, case series Review of References 56 Driver+PVI FIRM 7.7 0.77 0.48 66±9 0.75 56±8
2015 Tilz et al16 Manuscript Single center, case series PubMED 25 Driver+PVI FIRM 13.0 0.60 63±9 0.64 45.0±5 58±7
2016 Spitzer et al17 Manuscript Single center, case series PubMED 58 Driver+PVI FIRM 12.0 1.00 1.00 62±9 0.72 47.0±6 57±9
2016 Buch et al18 Manuscript Multicenter, case series PubMED 43 Driver+PVI FIRM 18.0 0.44 0.67 61 ±11 0.74 59±6
2016 Steinberg et al19 Manuscript Single center, case series PubMED 47 Driver+PVI FIRM 18.7 0.83 0.72 64±11 0.79 44.0±7 54±7
2016 Lin et al10 Manuscript Single center, controlled Cochrane 95 Driver+PVI Phase+similarity 17.7 1.00 56±9 0.79 39.9±7 58±7
2017 Miller et al25 Manuscript Single center, case series PubMED 170 Driver+PVI FIRM 15.0 0.63 0.43 59±12 0.79 52.0± 10 47 ±10
2017 Balouch et al21 Manuscript Single center, case series PubMED 27 Driver+PVI FIRM 12.0 1.00 0.52 64±9 0.82 46.0±8 53±7
2017 Kis et al22 Manuscript Single center, case series PubMED 38 Driver+PVI FIRM 12.0 1.00 0.53 63±11 0.63 46.0±7
2017 Knecht et al23 Manuscript Multicenter, case series PubMED 118 Driver+PVI ECVUE 12.0 1.00 0.00 64±8 0.74 43.0±6 60 ±9
2014 Atienza et al9 Manuscript Multicenter, randomized Cochrane 232 Driver only Dominant
frequency
12.0 0.00 0.24 54±12 0.73 40.0±6 60
2016 Berntsen et al24 Manuscript Single center, case series PubMED 33 Driver only FIRM 15.2 0.00 0.15 55±12 0.93 42.0±5
2017 Seitz et al11§ Manuscript Multicenter, controlled PubMED 152 Driver only Electrogram
dispersion
17.4 0.77 0.00 63±11 0.76 45.6±8 52±11
2012 Narayan et al7* Manuscript Control Control Control Control Control 9.1 0.66 0.25 61 ±8 0.96 43.0±6 55±12
2014 Atienza et al9 Manuscript Control Control Control Control Control 12.0 1.00 0.26 54± 10 0.83 42.5±7 60
2016 Lin et al10 Manuscript Control Control Control Control Control 17.7 1.00 54±9 0.77 39.0±6 58±8
2017 Seitz et al11§ Manuscript Control Control Control Control Control 17.4 0.81 0.00 58±11 0.74 42.4± 12 54±12

First authors are listed for manuscripts. Persistent AF, redo ablation, and male sex are presented as ratios. Age and LA size and ejection fraction are presented as mean±SD when available. Study size indicates the total cohort enrolled in the study. AF indicates atrial fibrillation; FIRM, Focal Impulse and Rotor Modulation; LA, left atrium; and PVI, pulmonary vein isolation. Study by Atienza et al,

is represented in 3 rows; study by Narayan et al,

*

Lin et al,

and Seitzet al,

§

is represented in 2 rows to show baseline information in each arm (ie, driver+PVI, driver only, and control).