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. 2019 Apr 12;13:13. doi: 10.3389/fnint.2019.00013

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Copyright © 2019 Minalyan, Gabrielyan, Pietra, Taché and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Photomicrographs of brain sections with tyrosine hydroxylase (TH) immunostaining at levels of the striatum (A,B) and substantia nigra (SN; C,D) from rats microinjected with vehicle (A,C) or 6-OHDA (B,D) in the right site of medial forebrain bundle (mfb). The immunostaining was processed about 6 weeks after mfb microinjection. Marked reductions in striatal fiber density (B) and nigral DA neurons (D) were shown on the side of 6-OHDA injection (right). SNc: substantia nigra pars compacta; SNr: SN pars reticulata; VTA: ventral tegmental area.